Comparing the effects of subchronic phencyclidine and medial prefrontal cortex dysfunction on cognitive tests relevant to schizophrenia

Rationale It is becoming increasingly clear that the development of treatments for cognitive symptoms of schizophrenia requires urgent attention, and that valid animal models of relevant impairments are required. With subchronic psychotomimetic agent phencyclidine (scPCP), a putative model of such i...

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Veröffentlicht in:	Psychopharmacology 2015-11, Vol.232 (21-22), p.3883-3897
Hauptverfasser:	McAllister, K. A. L., Mar, A. C., Theobald, D. E., Saksida, L. M., Bussey, T. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Biomedical and Life Sciences Biomedicine Brain Diseases - chemically induced Brain Diseases - psychology Cognition - drug effects Cognition disorders Cognitive ability Dosage and administration Excitatory Amino Acid Agonists Hallucinogens - pharmacology Ibotenic Acid Injections, Intraperitoneal Learning - drug effects Limbic System Male Memory - drug effects Neurosciences Original Investigation Pharmacology/Toxicology Phencyclidine Phencyclidine - pharmacology Physiological aspects Prefrontal Cortex Psychiatry Psychopharmacology Psychotropic drugs Rats Recognition (Psychology) - drug effects Schizophrenia Schizophrenic Psychology
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