Large fragment target enrichment and sequencing of the 4.4Mb major histocompatibility complex by region-specific extraction and HiSeq 2500

Due to the extensive polymorphism of the major histocompatibility complex (MHC), only limited progress has been made in high-resolution MHC sequencing, one of the initial requirements to elucidate the molecular immunopathology of several hundred MHC-associated diseases. We present an approach for se...

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Veröffentlicht in:Human immunology 2015-10, Vol.76, p.57-57
Hauptverfasser: Rabenstein, Hannah, Bangol, Barbara, Linke, Suzanne, Brumm, Riccardo, Poggel, Sebastian, Eck, Sebastian, Ott, Karl-Heinz, Dapprich, Johannes, Hirv, Kaimo
Format: Artikel
Sprache:eng
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