Kallikreins are involved in an miRNA network that contributes to prostate cancer progression

MicroRNAs (miRNAs) are short RNA nucleotides that negatively regulate their target genes. They are differentially expressed in prostate cancer. Kallikreins are genes that encode serine proteases and are dysregulated in cancer. We elucidated a miRNA-kallikrein network that can be involved in prostate...

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Veröffentlicht in:	Biological chemistry 2014-09, Vol.395 (9), p.991-1001
Hauptverfasser:	Samaan, Sara, Lichner, Zsuzsanna, Ding, Qiang, Saleh, Carol, Samuel, Joseph, Streutker, Catherine, Yousef, George M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence biochemical failure Disease Progression Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Regulatory Networks Gleason grade Humans Kallikreins - metabolism Male MicroRNAs - genetics MicroRNAs - metabolism microsatellite repeat Minisatellite Repeats - genetics Models, Biological Molecular Sequence Data Neoplasm Grading personalized medicine prostate-specific antigen Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology tumor markers
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