Differential Acute and Chronic Responses of Tumor Necrosis Factor-Deficient Mice to Experimental Brain Injury

The present study evaluated behavioral and histopathological outcome after controlled cortical impact (CCI) brain injury in mice deficient in tumor necrosis factor [TNF(-/-)] and their wild-type (wt) littermates. Mice were subjected to CCI brain injury [TNF(-/-), n = 10; wt, n = 10] or served as uni...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1999-07, Vol.96 (15), p.8721-8726
Hauptverfasser:	Scherbel, Uwe, Raghupathi, Ramesh, Nakamura, Michio, Saatman, Kathryn E., Trojanowski, John Q., Neugebauer, Edmund, Marino, Michael W., McIntosh, Tracy K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal Biological Sciences Brain - pathology Brain damage Brain injuries Brain Injuries - genetics Brain Injuries - physiopathology Cytokines Maze Learning Medical research Memory Memory disorders Mice Mice, Knockout Motor ability Motor Activity Neurology Neurons Neuroscience Physical trauma Postural Balance Rodents Time Factors Traumatic brain injury Tumor Necrosis Factor-alpha - deficiency Tumor Necrosis Factor-alpha - genetics Tumors
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