Lambert-Eaton Antibodies Inhibit Ca super(2+) Currents But Paradoxically Increase Exocytosis during Stimulus Trains in Bovine Adrenal Chromaffin Cells

Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease that affects neurotransmitter release at peripheral synapses. LEMS antibodies inhibit Ca super(2+) currents in excitable cells, but it is not known whether there are additional effects on stimulus-secretion coupling. The effect of LEM...

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Veröffentlicht in:The Journal of neuroscience 1999-05, Vol.19 (9), p.3384-3395
Hauptverfasser: Engisch, K L, Rich, M M, Cook, N, Nowycky, M C
Format: Artikel
Sprache:eng
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