Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria

Multiple dose pharmacokinetics of artemether and dihydroartemisinin were investigated in chinese patients treated for malaria. They received over 2 days either 4×80 mg artemether orally ( n=48) or 4×80–480 mg co-artemether ( n=40), a combination of artemether and lumefantrine (benflumetol). Lag time...

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Veröffentlicht in:	International journal of antimicrobial agents 1999-07, Vol.12 (2), p.151-158
Hauptverfasser:	van Agtmael, M.A, Cheng-Qi, Shan, Qing, Jiao Xiu, Mull, R, van Boxtel, C.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antimalarials - pharmacokinetics Antimalarials - therapeutic use Antiparasitic agents Artemether Artemisinins Auto-induction Benflumetol Biological and medical sciences China Double-Blind Method Drug Evaluation Drug Therapy, Combination Ethanolamines - pharmacokinetics Ethanolamines - therapeutic use Female Fluorenes - pharmacokinetics Fluorenes - therapeutic use General pharmacology Humans Lumefantrine Malaria Malaria, Falciparum - blood Malaria, Falciparum - drug therapy Male Medical sciences Middle Aged Models, Chemical Pharmacognosy. Homeopathy. Health food Pharmacokinetics Pharmacology. Drug treatments Plasmodium falciparum Sesquiterpenes - pharmacokinetics Sesquiterpenes - therapeutic use Time Factors
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