Electroacupuncture facilitates recovery of male sexual behavior in morphine withdrawal rats
The effect of electroacupuncture (EA) on the sexual behavior of male rats undergoing morphine withdrawal was studied by measuring various parameters of sexual behavior. In addition, the total serum testosterone (TST) concentrations in male rats at different times of morphine administration and absti...
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| Veröffentlicht in: | Neurochemical research 2004-02, Vol.29 (2), p.397-401 |
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| container_title | Neurochemical research |
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| creator | Cui, Guo-Hong Ren, Xiao-Wei Wu, Liu-Zhen Han, Ji-Sheng Cui, Cai-Lian |
| description | The effect of electroacupuncture (EA) on the sexual behavior of male rats undergoing morphine withdrawal was studied by measuring various parameters of sexual behavior. In addition, the total serum testosterone (TST) concentrations in male rats at different times of morphine administration and abstinence were measured. Acute and chronic administration of morphine severely inhibited the sexual behavior of the rats and lowered their TST concentrations. TST concentrations recovered to normal within 24 h after the last morphine injection, while sexual behavior remained suppressed for at least 7 days. Electroacupuncture (2/100 Hz alternately) administered once daily for 7 days during morphine withdrawal facilitated the recovery of male sexual behavior and increased TST concentrations to above normal. The effect of EA on sexual behavior may involve both neuronal and hormonal pathways. |
| doi_str_mv | 10.1023/B:NERE.0000013743.53827.ad |
| format | Article |
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In addition, the total serum testosterone (TST) concentrations in male rats at different times of morphine administration and abstinence were measured. Acute and chronic administration of morphine severely inhibited the sexual behavior of the rats and lowered their TST concentrations. TST concentrations recovered to normal within 24 h after the last morphine injection, while sexual behavior remained suppressed for at least 7 days. Electroacupuncture (2/100 Hz alternately) administered once daily for 7 days during morphine withdrawal facilitated the recovery of male sexual behavior and increased TST concentrations to above normal. 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In addition, the total serum testosterone (TST) concentrations in male rats at different times of morphine administration and abstinence were measured. Acute and chronic administration of morphine severely inhibited the sexual behavior of the rats and lowered their TST concentrations. TST concentrations recovered to normal within 24 h after the last morphine injection, while sexual behavior remained suppressed for at least 7 days. Electroacupuncture (2/100 Hz alternately) administered once daily for 7 days during morphine withdrawal facilitated the recovery of male sexual behavior and increased TST concentrations to above normal. 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| subjects | Animals Electroacupuncture Male Morphine - adverse effects Morphine - pharmacology Narcotics - adverse effects Narcotics - pharmacology Osmolar Concentration Rats Rats, Sprague-Dawley Sexual Behavior, Animal - drug effects Substance Withdrawal Syndrome - psychology Testosterone - blood |
| title | Electroacupuncture facilitates recovery of male sexual behavior in morphine withdrawal rats |
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