Antigen-specific accumulation of naïve, memory and effector CD4 T cells during anterior uveitis monitored by intravital microscopy

Uveitis is an immune-mediated ocular disease and a leading cause of blindness. We characterized a novel model of uveitis with intravital microscopy. Transfer of ovalbumin-specific T cells from DO11.10 spleen to BALB/c recipients and subsequent challenge with ovalbumin in the anterior chamber of the...

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Veröffentlicht in:	Cellular Immunology 2006, Vol.239 (1), p.49-60
Hauptverfasser:	Dullforce, Per A., Seitz, Greg W., Garman, Kiera L., Michael, Julie A., Crespo, Sergio M., Fleischman, Ross J., Planck, Stephen R., Parker, David C., Rosenbaum, James T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens - immunology CD4-Positive T-Lymphocytes - cytology CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism Cell Count Cell trafficking Female Gene Expression Regulation Hyaluronan Receptors - immunology Immunity, Innate - immunology Immunologic Memory - immunology Inflammation Integrin alpha2 - metabolism Intravital microscopy Mice Mice, Inbred BALB C Mice, Knockout Microscopy Ovalbumin - pharmacology T cells Uveitis, Anterior - chemically induced Uveitis, Anterior - immunology Uveitis, Anterior - metabolism Uveitis, Anterior - pathology
Online-Zugang:	Volltext
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