HIV Protease Inhibitors: Advances in Therapy and Adverse Reactions, Including Metabolic Complications

Protease inhibitors (PIs) effectively inhibit replication of the human immunodeficiency virus (HIV), and reduce mortality and prolong survival in patients with HIV infection. Newer PIs saquinavir (soft gelatin capsule) and amprenavir, as well as other PIs, may be effective when administered twice/da...

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Veröffentlicht in:	Pharmacotherapy 1999-03, Vol.19 (3), p.281-298
Hauptverfasser:	Kaul, Daniel R., Cinti, Sandro K., Carver, Peggy L., Kazanjian, Powel H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Drug Interactions HIV Infections - drug therapy HIV Protease Inhibitors - adverse effects HIV Protease Inhibitors - pharmacology HIV Protease Inhibitors - therapeutic use Human immunodeficiency virus 1 Humans Hyperlipidemias - chemically induced Indinavir - adverse effects Indinavir - pharmacology Indinavir - therapeutic use Lipodystrophy - chemically induced Medical sciences Nelfinavir - adverse effects Nelfinavir - pharmacology Nelfinavir - therapeutic use Pharmacology. Drug treatments Ritonavir - adverse effects Ritonavir - pharmacology Ritonavir - therapeutic use Saquinavir - adverse effects Saquinavir - pharmacology Saquinavir - therapeutic use
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