Atorvastatin along with imipenem attenuates acute lung injury in sepsis through decrease in inflammatory mediators and bacterial load

Lung is one of the vital organs which is affected during the sequential development of multi-organ dysfunction in sepsis. The purpose of the present study was to examine whether combined treatment with atorvastatin and imipenem could attenuate sepsis-induced lung injury in mice. Sepsis was induced b...

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Veröffentlicht in:European journal of pharmacology 2015-10, Vol.765, p.447-456
Hauptverfasser: Choudhury, Soumen, Kandasamy, Kannan, Maruti, Bhojane Somnath, Addison, M. Pule, Kasa, Jaya Kiran, Darzi, Sazad A., Singh, Thakur Uttam, Parida, Subhashree, Dash, Jeevan Ranjan, Singh, Vishakha, Mishra, Santosh Kumar
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Sprache:eng
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