Production of recombinant proteins in plant root exudates

The large-scale production of recombinant proteins in plants is limited by relatively low yields and difficulties in extraction and purification. These problems were addressed by engineering tobacco plants to continuously secrete recombinant proteins from their roots into a simple hydroponic medium....

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Veröffentlicht in:	Nature biotechnology 1999-05, Vol.17 (5), p.466-469
Hauptverfasser:	Raskin, Ilya, Borisjuk, Nikolai V, Borisjuk, Ludmyla G, Logendra, Sithes, Petersen, Frank, Gleba, Yuri
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Alkaline Phosphatase - genetics Alkaline Phosphatase - metabolism Animals Bioinformatics Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biotechnology Cloning, Molecular - methods Clostridium botulinum - enzymology Clostridium botulinum - genetics Green Fluorescent Proteins Humans Hydroponics Life Sciences Luminescent Proteins - genetics Luminescent Proteins - metabolism Nicotiana - genetics Nicotiana - growth & development Nicotiana - metabolism Nicotiana tabacum Placenta - enzymology Plant Roots - metabolism Plants, Genetically Modified Plants, Toxic Recombinant Proteins - genetics Recombinant Proteins - metabolism research-article Scyphozoa - genetics Scyphozoa - metabolism Xylan Endo-1,3-beta-Xylosidase Xylosidases - genetics Xylosidases - metabolism
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