Evaluation of the Central Activity of Hydroxydihydrocarvone

The central effects of hydroxydihydrocarvone (HC), an analogue of several monoterpenes, were evaluated in animal models. General behavior, locomotor activity, pentobarbital-induced sleeping time, pentylenetetrazol (PTZ)-induced convulsions, and acetic acid-induced writhing were evaluated in mice. Th...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2006, Vol.29(4), pp.811-812
Hauptverfasser:	Sousa, Damião Pergentino de, Oliveira, Fernando de Sousa, Almeida, Reinaldo Nóbrega de
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics - pharmacology Analgesics, Opioid - pharmacology Animals anticonvulsant activity Anticonvulsants - pharmacology antinociceptive activity carvone Central Nervous System Agents Convulsants Dose-Response Relationship, Drug essential oil hydroxydihydrocarvone Hypnotics and Sedatives - pharmacology Lethal Dose 50 Male Mice monoterpene Monoterpenes - pharmacology Morphine - pharmacology Motor Activity - drug effects Oils, Volatile - pharmacology Pain Measurement - drug effects Pentobarbital - pharmacology Pentylenetetrazole Seizures - chemically induced Seizures - prevention & control Sleep - drug effects
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