Intracellular Localization of the Fanconi Anemia Complementation Group A Protein

Mutations in the Fanconi anemia (FA) complementation group A (FANCA) gene leads to bone marrow failure, developmental abnormalities and cancer predisposition. To map the intracellular site of FANCA, we constructed a plasmid vector which linked in-frame the enhanced green fluorescent protein (EGFP cD...

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Veröffentlicht in:	Biochemical and biophysical research communications 1999-06, Vol.259 (3), p.594-599
Hauptverfasser:	Walsh, Christopher E., Yountz, Marcus R., Simpson, Dennis A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Cycle Cell Cycle Proteins Cell Nucleus - metabolism DNA-Binding Proteins Dose-Response Relationship, Drug Fanconi Anemia Complementation Group Proteins Fibroblasts Humans Mitomycin - pharmacology Mutagenesis Nuclear Proteins Nucleic Acid Synthesis Inhibitors - pharmacology Phenotype Proteins - analysis Recombinant Fusion Proteins
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