Effects of zearalenone on in utero development in rats

Zearalenone (ZE), an estrogenic mycotoxin produced by Fusarium graminearum or F. roseum, is one of the most common contaminants of cereal grains world-wide. The objective of this study was to determine the effects of ZE on in utero development of rats. Pregnant female Charles River Sprague-Dawley ra...

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Veröffentlicht in:	Food and chemical toxicology 2006-09, Vol.44 (9), p.1455-1465
Hauptverfasser:	Collins, Thomas F.X., Sprando, Robert L., Black, Thomas N., Olejnik, Nicholas, Eppley, Robert M., Alam, Hamida Z., Rorie, James, Ruggles, Dennis I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Drug-Induced Administration, Oral Animals Biological and medical sciences Bone Development - drug effects Developmental toxicity Dose-Response Relationship, Drug Embryology: invertebrates and vertebrates. Teratology Embryonic Development - drug effects Estrogenic mycotoxin Estrogens, Non-Steroidal - toxicity Female Fetal Death - chemically induced Fetal Development - drug effects Fetal Weight - drug effects Fundamental and applied biological sciences. Psychology Fusarium graminearum Genitalia - drug effects Genitalia - embryology Gonadal Steroid Hormones - blood Gonadotropins, Pituitary - blood Male Maternal Exposure Medical sciences No-Observed-Adverse-Effect Level Organ Size - drug effects Plant poisons toxicology Pregnancy Rat Rats Rats, Sprague-Dawley Reproduction - drug effects Sexual Maturation - drug effects Teratology. Teratogens Toxicology Zearalenone Zearalenone - toxicity
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