A 24-month dietary carcinogenicity study of DAG in mice

This study evaluated the possible carcinogenic effects of DAG (diacylglycerol) oil when given in the diet at levels up to 6.0% for 24 months to mice. Dietary fat was provided by DAG and/or the control article, TG (triacylglycerol oil). Dietary concentrations (% DAG/% TG) were 0%/6.0% (TG control), 1...

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Veröffentlicht in:	Food and chemical toxicology 2006, Vol.44 (1), p.122-137
Hauptverfasser:	Chengelis, Christopher P., Kirkpatrick, Jeannie B., Bruner, Richard H., Freshwater, Les, Morita, Osamu, Tamaki, Yasushi, Suzuki, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Biological and medical sciences Body Weight - drug effects carcinogenesis Carcinogenicity Carcinogenicity Tests Carcinogens - classification Carcinogens - toxicity cooking fats and oils Diacylglycerol diacylglycerols Diet Dietary dietary fat Diglycerides - chemistry Diglycerides - classification Diglycerides - toxicity dose response Dose-Response Relationship, Drug Eating - drug effects fat intake Fatty Acids - analysis Female histopathology Longevity - drug effects Male Medical sciences Mice Mouse No-Observed-Adverse-Effect Level Organ Size - drug effects Systemic toxicity toxicity testing Toxicology Triglycerides - chemistry Triglycerides - classification Triglycerides - toxicity weight gain
Online-Zugang:	Volltext
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