17{beta}-Estradiol Induces Down-Regulation of Cap43/NDRG1/Drg-1, a Putative Differentiation-Related and Metastasis Suppressor Gene, in Human Breast Cancer Cells

PURPOSE: Cap43 is known as a nickel- and calcium-inducible gene. In the present study, we examined whether 17{beta}-estradiol (E sub(2)) could affect the expression of Cap43 in breast cancer. Experimental Design: Real-time PCR, immunoblotting, and immunocytochemistry were used to examine the express...

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Veröffentlicht in:Clinical cancer research 2006-05, Vol.12 (10), p.3010-3018
Hauptverfasser: Fotovati, Abbas, Fujii, Teruhiko, Yamaguchi, Miki, Kage, Masayoshi, Shirouzu, Kazuo, Oie, Shinji, Basaki, Yuji, Ono, Mayumi, Yamana, Hideaki, Kuwano, Michihiko
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Sprache:eng
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