Genotoxicity Evaluation of Wood-Derived and Vegetable Oil-Derived Stanol Esters

Plant stanol esters from wood and vegetable oil sources were tested for genotoxicity in bacterial (Salmonella typhimurium) and mammalian cell (L5178Y) gene mutation assays and in a mammalian cell chromosome aberration assay (CHO cells). The two stanol ester formulations were tested separately at dos...

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Veröffentlicht in:	Regulatory toxicology and pharmacology 1999-04, Vol.29 (2), p.205-210
Hauptverfasser:	Turnbull, Duncan, Frankos, Vasilios H., van Delft, J.H.M., DeVogel, N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carcinogenicity Tests CHO Cells Chromosome Aberrations Cricetinae DNA Mutational Analysis Drug toxicity and drugs side effects treatment Evaluation Studies as Topic Medical sciences Mice Miscellaneous (drug allergy, mutagens, teratogens...) Mutagens - toxicity Pharmacology. Drug treatments Phytosterols - toxicity Plant Oils - chemistry Plant Oils - toxicity Salmonella typhimurium - drug effects Salmonella typhimurium - genetics Tumor Cells, Cultured Wood
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