Structural investigation of spherical hollow excipient Mannit Q by X-ray microtomography

[Display omitted] The structure of Mannit Q particles, an excipient made by spray-drying a d-mannitol solution, and Mannit Q tablets were investigated by synchrotron X-ray microtomography. The Mannit Q particles had a spherical shape with a hollow core. The shells of the particles consisted of fine...

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Veröffentlicht in:	International journal of pharmaceutics 2015-11, Vol.495 (1), p.140-143
Hauptverfasser:	Kajihara, Ryusuke, Noguchi, Shuji, Iwao, Yasunori, Yasuda, Yuki, Segawa, Megumi, Itai, Shigeru
Format:	Artikel
Sprache:	eng
Schlagworte:	Computed microtomography Crystallization Excipient particle Excipients - chemistry Mannitol Mannitol - chemistry Particle Size Synchrotron X-ray radiation Tablet Tablets X-Ray Microtomography
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