Nasopharyngeal carriage and macrolide resistance in Indigenous children with bronchiectasis randomized to long-term azithromycin or placebo

Although long-term azithromycin decreases exacerbation frequency in bronchiectasis, increased macrolide resistance is concerning. We investigated macrolide resistance determinants in a secondary analysis of a multicenter randomized controlled trial. Indigenous Australian children living in remote re...

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Veröffentlicht in:	European journal of clinical microbiology & infectious diseases 2015-11, Vol.34 (11), p.2275-2285
Hauptverfasser:	Hare, K. M., Grimwood, K., Chang, A. B., Chatfield, M. D., Valery, P. C., Leach, A. J., Smith-Vaughan, H. C., Morris, P. S., Byrnes, C. A., Torzillo, P. J., Cheng, A. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Australia Azithromycin - therapeutic use Bacteria - drug effects Bacteria - isolation & purification Bacterial Infections - drug therapy Bacterial Infections - microbiology Biomedical and Life Sciences Biomedicine Bronchiectasis - complications Carrier State - microbiology Child Child, Preschool Childrens health Drug Resistance, Bacterial Epidemiology Female Hospitals Humans Infant Internal Medicine Macrolides - pharmacology Macrolides - therapeutic use Male Medical Microbiology Medical research Nasopharynx - microbiology New Zealand Original Article Pacific Islander people Pacific Islands Pathogens Pediatrics Placebos - administration & dosage Population Groups Preventive medicine Secondary analysis Streptococcus infections
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