Mechanical strain affects some microRNA profiles in pre-oeteoblasts

MicroRNAs (miRNAs) are important regulators of cell proliferation, differentiation and function. Mechanical strain is an essential factor for osteoblast proliferation and differentiation. A previous study revealed that a physiological mechanical tensile strain of 2500 microstrain (με) at 0.5 Hz appl...

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Veröffentlicht in:	Cellular & molecular biology letters 2015-12, Vol.20 (4), p.586-596
Hauptverfasser:	Wang, Yang, Zou, Xianqiong, Guo, Yong, Wang, Lu, Liu, Yongming, Zeng, Qiangcheng, Zhang, Xizheng
Format:	Artikel
Sprache:	eng
Schlagworte:	2500 microstrain (με) Animals Bioinformatics Cell Differentiation - genetics Cell Line Gene Expression Profiling Mechanical strain Mechanoresponsive Mice Microarray MicroRNA MicroRNAs - genetics Mouse MC3T3-E1 preosteoblasts Oligonucleotide Array Sequence Analysis Osteoblast differentiation Osteoblasts - cytology Osteoblasts - physiology qRT-PCR Regulator Stress, Mechanical Transcriptome - genetics
Online-Zugang:	Volltext
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