Diacylglycerol Guides the Hopping of Clathrin-Coated Pits along Microtubules for Exo-Endocytosis Coupling

Many receptor-mediated endocytic processes are mediated by constitutive budding of clathrin-coated pits (CCPs) at spatially randomized sites before slowly pinching off from the plasma membrane (60–100 s). In contrast, clathrin-mediated endocytosis (CME) coupled with regulated exocytosis in excitable...

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Veröffentlicht in:	Developmental cell 2015-10, Vol.35 (1), p.120-130
Hauptverfasser:	Yuan, Tianyi, Liu, Lin, Zhang, Yongdeng, Wei, Lisi, Zhao, Shiqun, Zheng, Xiaolu, Huang, Xiaoshuai, Boulanger, Jerome, Gueudry, Charles, Lu, Jingze, Xie, Lihan, Du, Wen, Zong, Weijian, Yang, Lu, Salamero, Jean, Liu, Yanmei, Chen, Liangyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport Cell Membrane - metabolism Clathrin - metabolism Coated Pits, Cell-Membrane - physiology Cytoskeleton - metabolism Diglycerides - metabolism Electrophysiology Exocytosis - physiology Image Processing, Computer-Assisted Insulinoma - metabolism Insulinoma - pathology Membrane Fusion - physiology Membrane Proteins - metabolism Microtubules - physiology Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology Rats Tumor Cells, Cultured
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