Importance of low serum DNase I activity and polyspecific anti-neutrophil cytoplasmic antibodies in propylthiouracil-induced lupus-like syndrome

To study the role of deoxyribonuclease (DNase) I activity and ANCA in propylthiouracil (PTU)-induced lupus-like syndrome (LLS). We compared 36 SLE patients with 17 PTU-induced LLS patients diagnosed from 2008 to 2014. We studied ANCA profile (MPO, PR3, lactoferrin, CTG, elastase, bactericidal/permea...

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Veröffentlicht in:	Rheumatology (Oxford, England) England), 2015-11, Vol.54 (11), p.2061-2070
Hauptverfasser:	Gajic-Veljic, Mirjana, Bonaci-Nikolic, Branka, Lekic, Branislav, Skiljevic, Dusan, Ciric, Jasmina, Zoric, Svetlana, Stojimirovic, Biljana, Nikolic, Milos
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antibodies, Antineutrophil Cytoplasmic - blood Antithyroid Agents - adverse effects Antithyroid Agents - therapeutic use Biomarkers - blood Case-Control Studies Deoxyribonucleases - blood Female Humans Hyperthyroidism - drug therapy Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - chemically induced Lupus Erythematosus, Systemic - diagnosis Male Middle Aged Prevalence Prognosis Propylthiouracil - adverse effects Propylthiouracil - therapeutic use Retrospective Studies Syndrome Young Adult
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