Antibodies enhance CXCL10 production during RSV infection of infant and adult immune cells

•The influence of antibodies on innate immunity during RSV infection was investigated.•Antibodies reduce RSV infection rate, but enhance the innate immune response.•Antibodies enhance CXCL10, CXCL11, IFNα and IFNγ production in adult immune cells.•Immune cells from infants only show an antibody-depe...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2015-12, Vol.76 (2), p.458-464
Hauptverfasser:	Vissers, Marloes, Schreurs, Inge, Jans, Jop, Heldens, Jacco, de Groot, Ronald, de Jonge, Marien I., Ferwerda, Gerben
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies Antibodies - immunology Chemokine CXCL10 - genetics Chemokine CXCL10 - immunology CXCL10 Cytokines - biosynthesis Cytokines - immunology Enzyme-Linked Immunosorbent Assay Humans Immunity, Innate Infant Infants Innate immunity Respiratory Syncytial Virus Infections - immunology RSV Transcription, Genetic
Online-Zugang:	Volltext
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