Rubi Fructus (Rubus coreanus) activates the expression of thermogenic genes in vivo and in vitro

Objective: To investigate the anti-obesity effect of Rubi Fructus (RF) extract using brown adipose tissue (BAT) and primary brown preadipocytes in vivo and in vitro . Methods: Male C57BL/6 J mice ( n =5 per group) were fed a high-fat diet (HFD) for 10 weeks with or without RF. Brown preadipocytes fr...

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Veröffentlicht in:	International Journal of Obesity 2015-03, Vol.39 (3), p.456-464
Hauptverfasser:	Jeong, M-Y, Kim, H-L, Park, J, Jung, Y, Youn, D-H, Lee, J-H, Jin, J-S, So, H-S, Park, R, Kim, S-H, Kim, S-J, Hong, S-H, Um, J-Y
Format:	Artikel
Sprache:	eng
Schlagworte:	692/698/690/2816 692/699/1702/393 692/700/565 Adipocytes Adipocytes, Brown - metabolism Adipogenesis - drug effects Adipose tissue Adipose tissue (brown) Adipose Tissue, Brown - metabolism AMP AMP-activated protein kinase Animals Body fat Brown adipose tissue Care and treatment Cholesterol Dexamethasone Diet, High-Fat Differentiation Energy Epidemiology Fat cells Gene expression Gene Expression Regulation - drug effects Genes Health aspects Health Promotion and Disease Prevention High fat diet In vitro methods and tests In Vitro Techniques In vivo methods and tests Indomethacin Insulin Internal Medicine Kinases Male Materia medica, Vegetable Medical research Medicine Medicine & Public Health Medicine, Experimental Metabolic Diseases Metabolism Mice Mice, Inbred C57BL Mitochondria Modulation Obesity Obesity - pathology original-article Pharmacy Physiological aspects Plant extracts Plant Preparations - pharmacology Preadipocytes Pretreatment Prevention Proteins Public Health Rubus Rubus coreanus Serum levels siRNA Spleen Thermogenesis Thermogenesis - drug effects Thermogenesis - genetics Weight reduction
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