Different biological risk factors in young poor-prognosis and elderly patients with diffuse large B-cell lymphoma

Prognostically relevant risk factors in patients with diffuse large B-cell lymphoma (DLBCL) have predominantly been evaluated in elderly populations. We tested whether previously described risk factors are also valid in younger, poor-prognosis DLBCL patients. Paraffin-embedded samples from 112 patie...

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Veröffentlicht in:	Leukemia 2015-07, Vol.29 (7), p.1564-1570
Hauptverfasser:	Horn, H, Ziepert, M, Wartenberg, M, Staiger, A M, Barth, T F E, Bernd, H-W, Feller, A C, Klapper, W, Stuhlmann-Laeisz, C, Hummel, M, Stein, H, Lenze, D, Hartmann, S, Hansmann, M-L, Möller, P, Cogliatti, S, Pfreundschuh, M, Trümper, L, Loeffler, M, Glass, B, Schmitz, N, Ott, G, Rosenwald, A
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1990/291 692/499 692/53/2422 692/699/67/1990/291/1621/1915 692/700/1750/1976 Adolescent Adult Aged patients Analysis B-cell lymphoma Bcl-6 protein Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Cancer Cancer Research Care and treatment CD5 antigen Chemotherapy Critical Care Medicine Female Fluorescence Fluorescence in situ hybridization Follow-Up Studies Foxp1 protein Gene expression Geriatrics Hematology Humans Immunoenzyme Techniques Immunohistochemistry In Situ Hybridization, Fluorescence Intensive Interferon regulatory factor 4 Internal Medicine Lymphocytes B Lymphoma Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - metabolism Lymphoma, Large B-Cell, Diffuse - mortality Lymphoma, Large B-Cell, Diffuse - pathology Male Markers Medical prognosis Medicine Medicine & Public Health Middle Aged Myc protein Neoplasm Staging Non-Hodgkin's lymphoma Non-Hodgkin's lymphomas Older people Oncology original-article Paraffin Paraffins Plasmacytoid cells Prognosis Prospective Studies Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - metabolism Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - metabolism Risk analysis Risk Factors Survival Survival Rate Translocation Tumors Young Adult
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