“V-Plasty” technique using dual synthetic vascular grafts to reconstruct outflow channel in living donor liver transplantation

Background The reconstruction of outflow is a crucial step in living donor liver transplantation. This study describes a suitable technique that uses synthetic vascular conduits in presence of multiple draining veins of right lobe of liver and the outcome of the recipients to evaluate safety of usin...

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Veröffentlicht in:Surgery 2015-11, Vol.158 (5), p.1272-1282
Hauptverfasser: Jeng, Long-Bin, MD, Thorat, Ashok, MD, Li, Ping-Chun, MD, Li, Ming-Li, MD, Yang, Horng-Ren, MD, Yeh, Chun-Chieh, MD, Chen, Te-Hung, MD, Hsu, Chia-Hao, MD, Hsu, Shih-Chao, MD, Poon, Kin-Shing, MD
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container_end_page 1282
container_issue 5
container_start_page 1272
container_title Surgery
container_volume 158
creator Jeng, Long-Bin, MD
Thorat, Ashok, MD
Li, Ping-Chun, MD
Li, Ming-Li, MD
Yang, Horng-Ren, MD
Yeh, Chun-Chieh, MD
Chen, Te-Hung, MD
Hsu, Chia-Hao, MD
Hsu, Shih-Chao, MD
Poon, Kin-Shing, MD
description Background The reconstruction of outflow is a crucial step in living donor liver transplantation. This study describes a suitable technique that uses synthetic vascular conduits in presence of multiple draining veins of right lobe of liver and the outcome of the recipients to evaluate safety of using multiple synthetic grafts. Methods From March 2011 to September 2014, 325 patients underwent right lobe living donor liver transplantation. Expanded polytetra-fluoroethylene (ePTFE) grafts were used in total 155 of the liver allografts. Among these, 16 liver grafts required dual ePTFE grafts to reconstruct the outflow due to presence of multiple hepatic veins. Results The mean diameters for venous branches of segment 5 (V5) and 8 (V8) were 5 mm (range, 4–8 mm) and 7 mm (range, 5–9 mm). The mean diameter of inferior right hepatic veins was 8 mm (7–10 mm). All the recipients who received the right liver with dual ePTFE grafts showed satisfactory inflow and outflow immediately after reconstruction as measured by Doppler flowmetry. Postoperative ultrasonographic studies showed no disturbances in outflow. Protocol dynamic computed tomography performed in the second postoperative month showed 100% patency rates of the artificial grafts. At median follow-up of 24 months graft survival was achieved in 88%, whereas the patency rates of the ePTFE grafts were 100%. Conclusion The use of “V-Plasty” technique using dual artificial vascular grafts is a safe and feasible technique in the presence of various allograft venous anomalies & ensures a single venous channel for outflow reconstruction. Our study also suggests that ePTFE graft may be a useful interposition material without serious complications.
doi_str_mv 10.1016/j.surg.2015.03.018
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This study describes a suitable technique that uses synthetic vascular conduits in presence of multiple draining veins of right lobe of liver and the outcome of the recipients to evaluate safety of using multiple synthetic grafts. Methods From March 2011 to September 2014, 325 patients underwent right lobe living donor liver transplantation. Expanded polytetra-fluoroethylene (ePTFE) grafts were used in total 155 of the liver allografts. Among these, 16 liver grafts required dual ePTFE grafts to reconstruct the outflow due to presence of multiple hepatic veins. Results The mean diameters for venous branches of segment 5 (V5) and 8 (V8) were 5 mm (range, 4–8 mm) and 7 mm (range, 5–9 mm). The mean diameter of inferior right hepatic veins was 8 mm (7–10 mm). All the recipients who received the right liver with dual ePTFE grafts showed satisfactory inflow and outflow immediately after reconstruction as measured by Doppler flowmetry. Postoperative ultrasonographic studies showed no disturbances in outflow. Protocol dynamic computed tomography performed in the second postoperative month showed 100% patency rates of the artificial grafts. At median follow-up of 24 months graft survival was achieved in 88%, whereas the patency rates of the ePTFE grafts were 100%. Conclusion The use of “V-Plasty” technique using dual artificial vascular grafts is a safe and feasible technique in the presence of various allograft venous anomalies &amp; ensures a single venous channel for outflow reconstruction. Our study also suggests that ePTFE graft may be a useful interposition material without serious complications.</description><identifier>ISSN: 0039-6060</identifier><identifier>EISSN: 1532-7361</identifier><identifier>DOI: 10.1016/j.surg.2015.03.018</identifier><identifier>PMID: 25920910</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Aged ; Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation - methods ; Cohort Studies ; End Stage Liver Disease - etiology ; End Stage Liver Disease - pathology ; End Stage Liver Disease - surgery ; Feasibility Studies ; Female ; Graft Survival ; Hepatic Veins - surgery ; Humans ; Liver Transplantation - methods ; Living Donors ; Male ; Middle Aged ; Polytetrafluoroethylene ; Surgery ; Treatment Outcome</subject><ispartof>Surgery, 2015-11, Vol.158 (5), p.1272-1282</ispartof><rights>Elsevier Inc.</rights><rights>2015 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c547t-91ea9a1c5ccb621d38a0a3d18410a5b4565ff012a0724504f00e7633a52339bd3</citedby><cites>FETCH-LOGICAL-c547t-91ea9a1c5ccb621d38a0a3d18410a5b4565ff012a0724504f00e7633a52339bd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S003960601500210X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25920910$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jeng, Long-Bin, MD</creatorcontrib><creatorcontrib>Thorat, Ashok, MD</creatorcontrib><creatorcontrib>Li, Ping-Chun, MD</creatorcontrib><creatorcontrib>Li, Ming-Li, MD</creatorcontrib><creatorcontrib>Yang, Horng-Ren, MD</creatorcontrib><creatorcontrib>Yeh, Chun-Chieh, MD</creatorcontrib><creatorcontrib>Chen, Te-Hung, MD</creatorcontrib><creatorcontrib>Hsu, Chia-Hao, MD</creatorcontrib><creatorcontrib>Hsu, Shih-Chao, MD</creatorcontrib><creatorcontrib>Poon, Kin-Shing, MD</creatorcontrib><title>“V-Plasty” technique using dual synthetic vascular grafts to reconstruct outflow channel in living donor liver transplantation</title><title>Surgery</title><addtitle>Surgery</addtitle><description>Background The reconstruction of outflow is a crucial step in living donor liver transplantation. This study describes a suitable technique that uses synthetic vascular conduits in presence of multiple draining veins of right lobe of liver and the outcome of the recipients to evaluate safety of using multiple synthetic grafts. Methods From March 2011 to September 2014, 325 patients underwent right lobe living donor liver transplantation. Expanded polytetra-fluoroethylene (ePTFE) grafts were used in total 155 of the liver allografts. Among these, 16 liver grafts required dual ePTFE grafts to reconstruct the outflow due to presence of multiple hepatic veins. Results The mean diameters for venous branches of segment 5 (V5) and 8 (V8) were 5 mm (range, 4–8 mm) and 7 mm (range, 5–9 mm). The mean diameter of inferior right hepatic veins was 8 mm (7–10 mm). All the recipients who received the right liver with dual ePTFE grafts showed satisfactory inflow and outflow immediately after reconstruction as measured by Doppler flowmetry. Postoperative ultrasonographic studies showed no disturbances in outflow. Protocol dynamic computed tomography performed in the second postoperative month showed 100% patency rates of the artificial grafts. At median follow-up of 24 months graft survival was achieved in 88%, whereas the patency rates of the ePTFE grafts were 100%. Conclusion The use of “V-Plasty” technique using dual artificial vascular grafts is a safe and feasible technique in the presence of various allograft venous anomalies &amp; ensures a single venous channel for outflow reconstruction. Our study also suggests that ePTFE graft may be a useful interposition material without serious complications.</description><subject>Adult</subject><subject>Aged</subject><subject>Blood Vessel Prosthesis</subject><subject>Blood Vessel Prosthesis Implantation - methods</subject><subject>Cohort Studies</subject><subject>End Stage Liver Disease - etiology</subject><subject>End Stage Liver Disease - pathology</subject><subject>End Stage Liver Disease - surgery</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Graft Survival</subject><subject>Hepatic Veins - surgery</subject><subject>Humans</subject><subject>Liver Transplantation - methods</subject><subject>Living Donors</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Polytetrafluoroethylene</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><issn>0039-6060</issn><issn>1532-7361</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc2KFDEUhQtRnHb0BVxIlm6q5t6kUj8gggyjDgwo-IO7kE6lutOmkzY_Lb0bfA59uXkSq6ZHFy5cXS6cc7j3O0XxFKFCwOZsU8UcVhUF5BWwCrC7VyyQM1q2rMH7xQKA9WUDDZwUj2LcAEBfY_ewOKG8p9AjLIofN9c_P5fvrYzpcHP9iySt1s58y5rkaNyKDFlaEg8urXUyiuxlVNnKQFZBjimS5EnQyruYQlaJ-JxG678TtZbOaUuMI9bsb3O882FedCApSBd3Vrokk_HucfFglDbqJ3fztPj0-uLj-dvy6t2by_NXV6XidZvKHrXsJSqu1LKhOLBOgmQDdjWC5MuaN3wcAamEltYc6hFAtw1jklPG-uXATovnx9xd8NODMYmtiUrb6RDtcxTYUuyxo9hNUnqUquBjDHoUu2C2MhwEgpjZi42Y2YuZvQAm4Nb07C4_L7d6-Gv5A3sSvDgK9PTl3uggojLaKT2YCWISgzf_z3_5j11Z44yS9qs-6LjxObiJn0ARqQDxYW5_Lh85AEX4wn4DLzSu2Q</recordid><startdate>20151101</startdate><enddate>20151101</enddate><creator>Jeng, Long-Bin, MD</creator><creator>Thorat, Ashok, MD</creator><creator>Li, Ping-Chun, MD</creator><creator>Li, Ming-Li, MD</creator><creator>Yang, Horng-Ren, MD</creator><creator>Yeh, Chun-Chieh, MD</creator><creator>Chen, Te-Hung, MD</creator><creator>Hsu, Chia-Hao, MD</creator><creator>Hsu, Shih-Chao, MD</creator><creator>Poon, Kin-Shing, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20151101</creationdate><title>“V-Plasty” technique using dual synthetic vascular grafts to reconstruct outflow channel in living donor liver transplantation</title><author>Jeng, Long-Bin, MD ; 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This study describes a suitable technique that uses synthetic vascular conduits in presence of multiple draining veins of right lobe of liver and the outcome of the recipients to evaluate safety of using multiple synthetic grafts. Methods From March 2011 to September 2014, 325 patients underwent right lobe living donor liver transplantation. Expanded polytetra-fluoroethylene (ePTFE) grafts were used in total 155 of the liver allografts. Among these, 16 liver grafts required dual ePTFE grafts to reconstruct the outflow due to presence of multiple hepatic veins. Results The mean diameters for venous branches of segment 5 (V5) and 8 (V8) were 5 mm (range, 4–8 mm) and 7 mm (range, 5–9 mm). The mean diameter of inferior right hepatic veins was 8 mm (7–10 mm). All the recipients who received the right liver with dual ePTFE grafts showed satisfactory inflow and outflow immediately after reconstruction as measured by Doppler flowmetry. Postoperative ultrasonographic studies showed no disturbances in outflow. Protocol dynamic computed tomography performed in the second postoperative month showed 100% patency rates of the artificial grafts. At median follow-up of 24 months graft survival was achieved in 88%, whereas the patency rates of the ePTFE grafts were 100%. Conclusion The use of “V-Plasty” technique using dual artificial vascular grafts is a safe and feasible technique in the presence of various allograft venous anomalies &amp; ensures a single venous channel for outflow reconstruction. Our study also suggests that ePTFE graft may be a useful interposition material without serious complications.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25920910</pmid><doi>10.1016/j.surg.2015.03.018</doi><tpages>11</tpages></addata></record>
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Adult
Aged
Blood Vessel Prosthesis
Blood Vessel Prosthesis Implantation - methods
Cohort Studies
End Stage Liver Disease - etiology
End Stage Liver Disease - pathology
End Stage Liver Disease - surgery
Feasibility Studies
Female
Graft Survival
Hepatic Veins - surgery
Humans
Liver Transplantation - methods
Living Donors
Male
Middle Aged
Polytetrafluoroethylene
Surgery
Treatment Outcome
title “V-Plasty” technique using dual synthetic vascular grafts to reconstruct outflow channel in living donor liver transplantation
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