Analysis of human IgE epitope of Der f 2 with anti-Der f 2 mouse monoclonal antibodies

Der f 2 is one of the major mite allergens recognized by human IgE antibodies of allergic patients. Using five anti-Der f 2 mouse monoclonal antibodies, human IgE epitopes of Der f 2 were analyzed. Among them, two monoclonal antibodies 15E11 and 13A4 inhibited the binding between Der f 2 and human I...

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Veröffentlicht in:	Molecular immunology 1999, Vol.36 (1), p.53-60
Hauptverfasser:	Nishiyama, Chiharu, Hatanaka, Hideki, Ichikawa, Saori, Fukada, Minako, Akagawa-Chihara, Midori, Yuuki, Toshifumi, Yokota, Toyokazu, Inagaki, Fuyuhiko, Okumura, Yasushi
Format:	Artikel
Sprache:	eng
Schlagworte:	3-D structure Allergens - immunology Amino Acid Sequence Animals Antibodies, Monoclonal - immunology Antigens - immunology Antigens, Dermatophagoides Der f 2 Dermatophagoidesfarinae Epitope Mapping Glycoproteins - genetics Glycoproteins - immunology Humans IgE-epitope Immunodominant Epitopes - immunology Immunoglobulin E - immunology Mice Mite allergen Mites Molecular Sequence Data Mutation Site-directed mutagenesis
Online-Zugang:	Volltext
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