Optimal and maximin sample sizes for multicentre cost-effectiveness trials

This paper deals with the optimal sample sizes for a multicentre trial in which the cost-effectiveness of two treatments in terms of net monetary benefit is studied. A bivariate random-effects model, with the treatment-by-centre interaction effect being random and the main effect of centres fixed or...

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Veröffentlicht in:	Statistical methods in medical research 2015-10, Vol.24 (5), p.513-539
Hauptverfasser:	Manju, Md. Abu, Candel, Math JJM, Berger, Martijn PF
Format:	Artikel
Sprache:	eng
Schlagworte:	Cost-Benefit Analysis Data Interpretation, Statistical Health Care Costs - statistics & numerical data Humans Models, Statistical Multicenter Studies as Topic - methods Randomized Controlled Trials as Topic - methods Sample Size
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