A single nanoparticle-based sensor for hydrogen peroxide (H2O2) via cytochrome c-mediated plasmon resonance energy transfer
Herein, we report a novel method for H2O2 detection based on a single plasmonic nanoprobe via cytochrome c (Cyt c)-mediated plasmon resonance energy transfer (PRET). Dynamic spectral changes were observed in the fingerprint quenching dip of a single plasmonic nanoprobe in response to changes in the...
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Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2015-01, Vol.51 (84), p.15370-15373 |
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creator | Kim, Yura Park, Ji Youn Kim, Hye Young Lee, Minzae Yi, Jongheop Choi, Inhee |
description | Herein, we report a novel method for H2O2 detection based on a single plasmonic nanoprobe via cytochrome c (Cyt c)-mediated plasmon resonance energy transfer (PRET). Dynamic spectral changes were observed in the fingerprint quenching dip of a single plasmonic nanoprobe in response to changes in the redox state of Cyt c, induced by H2O2. Based on the changes in the spectral profile of the single plasmonic nanoprobe, H2O2 was successfully detected in a wide concentration range from 100 mM to 10 nM, including physiologically relevant micromolar and nanomolar concentrations. |
doi_str_mv | 10.1039/c5cc05327g |
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Dynamic spectral changes were observed in the fingerprint quenching dip of a single plasmonic nanoprobe in response to changes in the redox state of Cyt c, induced by H2O2. 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Based on the changes in the spectral profile of the single plasmonic nanoprobe, H2O2 was successfully detected in a wide concentration range from 100 mM to 10 nM, including physiologically relevant micromolar and nanomolar concentrations.</description><subject>Cytochromes c - chemistry</subject><subject>Cytochromes c - metabolism</subject><subject>Fluorescence Resonance Energy Transfer</subject><subject>Gold - chemistry</subject><subject>Hydrogen Peroxide - analysis</subject><subject>Hydrogen Peroxide - metabolism</subject><subject>Metal Nanoparticles - chemistry</subject><subject>Oxidation-Reduction</subject><issn>1359-7345</issn><issn>1364-548X</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1Lw0AQhhdRbK1e_AGyxypEs1_5OJagrVDoRcFb2GwmaSTZjbupGPzzbm11YJg5PPPCPAhdk_CehCx9UEKpUDAa1ydoSljEA8GTt9P9LtIgZlxM0IVz76EvIpJzNKGRp1nIpuh7gV2j6xawltr00g6NaiEopIMSO9DOWFz53o6lNTVo3IM1X00JeL6iG3qLPxuJ1TgYtbWmA6yCDspGDv66b6XrjMYWnPHhCjBosPWIByu1q8BeorNKtg6ujnOGXp8eX7JVsN4sn7PFOlBMsCEQALTkKo25VIzEKSeEJ4SVJGIREzGpGKhSlYSmUVFVSZF4FTxOpKQRoQQiNkPzQ25vzccO3JB3jVPQtlKD2bmcxJQwHoci9OjdAVXWOGehynvbdNKOOQnzvew8E1n2K3vp4Ztj7q7wX_-jf3bZD_fGeoI</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Kim, Yura</creator><creator>Park, Ji Youn</creator><creator>Kim, Hye Young</creator><creator>Lee, Minzae</creator><creator>Yi, Jongheop</creator><creator>Choi, Inhee</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150101</creationdate><title>A single nanoparticle-based sensor for hydrogen peroxide (H2O2) via cytochrome c-mediated plasmon resonance energy transfer</title><author>Kim, Yura ; Park, Ji Youn ; Kim, Hye Young ; Lee, Minzae ; Yi, Jongheop ; Choi, Inhee</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c353t-5ee2d4c974ac31794114813d16363571f3ecdcd1296bff8b8532478aa26121e63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Cytochromes c - chemistry</topic><topic>Cytochromes c - metabolism</topic><topic>Fluorescence Resonance Energy Transfer</topic><topic>Gold - chemistry</topic><topic>Hydrogen Peroxide - analysis</topic><topic>Hydrogen Peroxide - metabolism</topic><topic>Metal Nanoparticles - chemistry</topic><topic>Oxidation-Reduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Yura</creatorcontrib><creatorcontrib>Park, Ji Youn</creatorcontrib><creatorcontrib>Kim, Hye Young</creatorcontrib><creatorcontrib>Lee, Minzae</creatorcontrib><creatorcontrib>Yi, Jongheop</creatorcontrib><creatorcontrib>Choi, Inhee</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Yura</au><au>Park, Ji Youn</au><au>Kim, Hye Young</au><au>Lee, Minzae</au><au>Yi, Jongheop</au><au>Choi, Inhee</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A single nanoparticle-based sensor for hydrogen peroxide (H2O2) via cytochrome c-mediated plasmon resonance energy transfer</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><addtitle>Chem Commun (Camb)</addtitle><date>2015-01-01</date><risdate>2015</risdate><volume>51</volume><issue>84</issue><spage>15370</spage><epage>15373</epage><pages>15370-15373</pages><issn>1359-7345</issn><issn>1364-548X</issn><eissn>1364-548X</eissn><abstract>Herein, we report a novel method for H2O2 detection based on a single plasmonic nanoprobe via cytochrome c (Cyt c)-mediated plasmon resonance energy transfer (PRET). 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source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
subjects | Cytochromes c - chemistry Cytochromes c - metabolism Fluorescence Resonance Energy Transfer Gold - chemistry Hydrogen Peroxide - analysis Hydrogen Peroxide - metabolism Metal Nanoparticles - chemistry Oxidation-Reduction |
title | A single nanoparticle-based sensor for hydrogen peroxide (H2O2) via cytochrome c-mediated plasmon resonance energy transfer |
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