Hair Selenium Levels of School Children in Kashin–Beck Disease Endemic Areas in Tibet, China
Previous studies have shown that the selenium (Se) deficiency is an important factor for the etiology of Kashin–Beck disease (KBD). Although KBD is presently controlled in most regions of China, it is still active in the Tibetan Plateau. The present study aimed to assess the nutritional status of se...
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| Veröffentlicht in: | Biological trace element research 2015-11, Vol.168 (1), p.25-32 |
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| creator | Chen, Zhuo Li, Hairong Yang, Linsheng Wang, Wuyi Li, Yonghua Gong, Hongqiang Guo, Min Nima, Cangjue Zhao, Shengcheng Wang, Jing Ye, Bixiong Danzeng, Sangbu Deji, Yangzong |
| description | Previous studies have shown that the selenium (Se) deficiency is an important factor for the etiology of Kashin–Beck disease (KBD). Although KBD is presently controlled in most regions of China, it is still active in the Tibetan Plateau. The present study aimed to assess the nutritional status of selenium in school children by using the Se level in hair as a biomarker in KBD endemic areas of Lhasa in Tibet, China. Hair samples of 155 school children aged 6–15 years were collected in both KBD areas and non-KBD areas of Lhasa in 2013. The Se level in the hair samples was determined by inductive coupled plasma mass spectrometry (ICP-MS). The average concentration of Se in children’s hair was 0.232 μg/g in KBD areas of Lhasa, which was significantly higher than the data reported decades ago. A significant difference in hair Se was observed between the boys (0.255 μg/g) and the girls (0.222 μg/g) in the studied KBD areas (
P
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| doi_str_mv | 10.1007/s12011-015-0333-4 |
| format | Article |
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P
< 0.01, Mann–Whitney
U
test), but hair Se did not vary by age or region. School children in KBD endemic areas in Lhasa likely have improved Se status as a result of high Se content staple food substitution with the enforcement of Free Education Policy and Nutrition Improvement Plan in Tibet. Nevertheless, there were still 20.3 % of students with low Se status (hair Se <0.20 μg/g), which showed that Se status of school children was also partly affected by low Se environment in KBD endemic areas of Lhasa.</description><identifier>ISSN: 0163-4984</identifier><identifier>EISSN: 1559-0720</identifier><identifier>DOI: 10.1007/s12011-015-0333-4</identifier><identifier>PMID: 25910897</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adolescent ; Biochemistry ; Biomedical and Life Sciences ; Biotechnology ; Bone diseases ; Child ; Children ; Children & youth ; Endemic Diseases ; Environment ; Female ; Hair ; Hair - chemistry ; Hair analysis ; Humans ; Kashin-Beck Disease - metabolism ; Life Sciences ; Male ; Mass Spectrometry ; Nutrition ; Nutrition assessment ; Nutritional status ; Oncology ; Quality Control ; Reproducibility of Results ; Selenium ; Selenium - analysis ; Sex Characteristics ; Tibet - epidemiology ; Trace elements</subject><ispartof>Biological trace element research, 2015-11, Vol.168 (1), p.25-32</ispartof><rights>Springer Science+Business Media New York 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c485t-9fde9bc46e4e7bfa50d195b720ec92a78c729db99635ff06038801ecd47f4ac73</citedby><cites>FETCH-LOGICAL-c485t-9fde9bc46e4e7bfa50d195b720ec92a78c729db99635ff06038801ecd47f4ac73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12011-015-0333-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12011-015-0333-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25910897$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chen, Zhuo</creatorcontrib><creatorcontrib>Li, Hairong</creatorcontrib><creatorcontrib>Yang, Linsheng</creatorcontrib><creatorcontrib>Wang, Wuyi</creatorcontrib><creatorcontrib>Li, Yonghua</creatorcontrib><creatorcontrib>Gong, Hongqiang</creatorcontrib><creatorcontrib>Guo, Min</creatorcontrib><creatorcontrib>Nima, Cangjue</creatorcontrib><creatorcontrib>Zhao, Shengcheng</creatorcontrib><creatorcontrib>Wang, Jing</creatorcontrib><creatorcontrib>Ye, Bixiong</creatorcontrib><creatorcontrib>Danzeng, Sangbu</creatorcontrib><creatorcontrib>Deji, Yangzong</creatorcontrib><title>Hair Selenium Levels of School Children in Kashin–Beck Disease Endemic Areas in Tibet, China</title><title>Biological trace element research</title><addtitle>Biol Trace Elem Res</addtitle><addtitle>Biol Trace Elem Res</addtitle><description>Previous studies have shown that the selenium (Se) deficiency is an important factor for the etiology of Kashin–Beck disease (KBD). Although KBD is presently controlled in most regions of China, it is still active in the Tibetan Plateau. The present study aimed to assess the nutritional status of selenium in school children by using the Se level in hair as a biomarker in KBD endemic areas of Lhasa in Tibet, China. Hair samples of 155 school children aged 6–15 years were collected in both KBD areas and non-KBD areas of Lhasa in 2013. The Se level in the hair samples was determined by inductive coupled plasma mass spectrometry (ICP-MS). The average concentration of Se in children’s hair was 0.232 μg/g in KBD areas of Lhasa, which was significantly higher than the data reported decades ago. A significant difference in hair Se was observed between the boys (0.255 μg/g) and the girls (0.222 μg/g) in the studied KBD areas (
P
< 0.01, Mann–Whitney
U
test), but hair Se did not vary by age or region. School children in KBD endemic areas in Lhasa likely have improved Se status as a result of high Se content staple food substitution with the enforcement of Free Education Policy and Nutrition Improvement Plan in Tibet. Nevertheless, there were still 20.3 % of students with low Se status (hair Se <0.20 μg/g), which showed that Se status of school children was also partly affected by low Se environment in KBD endemic areas of Lhasa.</description><subject>Adolescent</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Bone diseases</subject><subject>Child</subject><subject>Children</subject><subject>Children & youth</subject><subject>Endemic Diseases</subject><subject>Environment</subject><subject>Female</subject><subject>Hair</subject><subject>Hair - chemistry</subject><subject>Hair analysis</subject><subject>Humans</subject><subject>Kashin-Beck Disease - metabolism</subject><subject>Life Sciences</subject><subject>Male</subject><subject>Mass Spectrometry</subject><subject>Nutrition</subject><subject>Nutrition assessment</subject><subject>Nutritional status</subject><subject>Oncology</subject><subject>Quality Control</subject><subject>Reproducibility of Results</subject><subject>Selenium</subject><subject>Selenium - 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Academic</collection><jtitle>Biological trace element research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Zhuo</au><au>Li, Hairong</au><au>Yang, Linsheng</au><au>Wang, Wuyi</au><au>Li, Yonghua</au><au>Gong, Hongqiang</au><au>Guo, Min</au><au>Nima, Cangjue</au><au>Zhao, Shengcheng</au><au>Wang, Jing</au><au>Ye, Bixiong</au><au>Danzeng, Sangbu</au><au>Deji, Yangzong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hair Selenium Levels of School Children in Kashin–Beck Disease Endemic Areas in Tibet, China</atitle><jtitle>Biological trace element research</jtitle><stitle>Biol Trace Elem Res</stitle><addtitle>Biol Trace Elem Res</addtitle><date>2015-11-01</date><risdate>2015</risdate><volume>168</volume><issue>1</issue><spage>25</spage><epage>32</epage><pages>25-32</pages><issn>0163-4984</issn><eissn>1559-0720</eissn><abstract>Previous studies have shown that the selenium (Se) deficiency is an important factor for the etiology of Kashin–Beck disease (KBD). Although KBD is presently controlled in most regions of China, it is still active in the Tibetan Plateau. The present study aimed to assess the nutritional status of selenium in school children by using the Se level in hair as a biomarker in KBD endemic areas of Lhasa in Tibet, China. Hair samples of 155 school children aged 6–15 years were collected in both KBD areas and non-KBD areas of Lhasa in 2013. The Se level in the hair samples was determined by inductive coupled plasma mass spectrometry (ICP-MS). The average concentration of Se in children’s hair was 0.232 μg/g in KBD areas of Lhasa, which was significantly higher than the data reported decades ago. A significant difference in hair Se was observed between the boys (0.255 μg/g) and the girls (0.222 μg/g) in the studied KBD areas (
P
< 0.01, Mann–Whitney
U
test), but hair Se did not vary by age or region. School children in KBD endemic areas in Lhasa likely have improved Se status as a result of high Se content staple food substitution with the enforcement of Free Education Policy and Nutrition Improvement Plan in Tibet. Nevertheless, there were still 20.3 % of students with low Se status (hair Se <0.20 μg/g), which showed that Se status of school children was also partly affected by low Se environment in KBD endemic areas of Lhasa.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>25910897</pmid><doi>10.1007/s12011-015-0333-4</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Biochemistry Biomedical and Life Sciences Biotechnology Bone diseases Child Children Children & youth Endemic Diseases Environment Female Hair Hair - chemistry Hair analysis Humans Kashin-Beck Disease - metabolism Life Sciences Male Mass Spectrometry Nutrition Nutrition assessment Nutritional status Oncology Quality Control Reproducibility of Results Selenium Selenium - analysis Sex Characteristics Tibet - epidemiology Trace elements |
| title | Hair Selenium Levels of School Children in Kashin–Beck Disease Endemic Areas in Tibet, China |
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