Determination of Pyrolysis Products of Smoked Methamphetamine Mixed with Tobacco by Tandem Mass Spectrometry
This study examines the pyrolysis products of smoked methamphetamine mixed with tobacco that was trapped with a C8 adsorbent cartridge and then detected by gas chromatography-tandem mass spectrometry. According to the results, the mainstream smoke contains 2-methylpropyl-benzene, 2-chloropropyl-benz...
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| Veröffentlicht in: | Journal of analytical toxicology 1999-01, Vol.23 (1), p.41-45 |
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| creator | Lee, Maw-Rong Jeng, Jsuey Hsiang, Wei-Shin Hwang, Bao-Huey |
| description | This study examines the pyrolysis products of smoked methamphetamine mixed with tobacco that was trapped with a C8 adsorbent cartridge and then detected by gas chromatography-tandem mass spectrometry. According to the results, the mainstream smoke contains 2-methylpropyl-benzene, 2-chloropropyl-benzene, 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one, 3-ethyl-phenol, methamphetamine, dimethylamphetamine, hydroquinone, 3-methyl-5-(1-methylethyl)-methylcarbamate phenol, N-methyl-N-(2-phenylethyl)-acetamide, 4-(3-hydroxy-1-butenyl)-3,5,5-trimethyl-2-cyclohexene-1-one, propanoic acid, N-acetylmethamphetamine, phenyl ester, and furfurylmethylamphetamine. In addition, the compounds in sidestream smoke are 2-propenyl benzene, phenylacetone, methamphetamine, dimethylamphetamine, benzyl methyl ketoxime, 3,4-dihydro-2-naphthalenone, N-folmyamphetamine, N-acetylamphetamine, bibenzyl, N-folmylmethamphetamine, N-acetylmethamphetamine, N-propionymethamphetamine, and furfurylmethylamphetamine. Moreover, the presence of methamphetamine promotes the oxidation of the tobacco components. |
| doi_str_mv | 10.1093/jat/23.1.41 |
| format | Article |
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According to the results, the mainstream smoke contains 2-methylpropyl-benzene, 2-chloropropyl-benzene, 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one, 3-ethyl-phenol, methamphetamine, dimethylamphetamine, hydroquinone, 3-methyl-5-(1-methylethyl)-methylcarbamate phenol, N-methyl-N-(2-phenylethyl)-acetamide, 4-(3-hydroxy-1-butenyl)-3,5,5-trimethyl-2-cyclohexene-1-one, propanoic acid, N-acetylmethamphetamine, phenyl ester, and furfurylmethylamphetamine. In addition, the compounds in sidestream smoke are 2-propenyl benzene, phenylacetone, methamphetamine, dimethylamphetamine, benzyl methyl ketoxime, 3,4-dihydro-2-naphthalenone, N-folmyamphetamine, N-acetylamphetamine, bibenzyl, N-folmylmethamphetamine, N-acetylmethamphetamine, N-propionymethamphetamine, and furfurylmethylamphetamine. Moreover, the presence of methamphetamine promotes the oxidation of the tobacco components.</description><identifier>ISSN: 0146-4760</identifier><identifier>EISSN: 1945-2403</identifier><identifier>DOI: 10.1093/jat/23.1.41</identifier><identifier>PMID: 10022208</identifier><identifier>CODEN: JATOD3</identifier><language>eng</language><publisher>Niles, IL: Oxford University Press</publisher><subject>Analysis ; Biological and medical sciences ; Drug Interactions ; Gas Chromatography-Mass Spectrometry ; General pharmacology ; Hot Temperature ; Medical sciences ; Methamphetamine - analysis ; Methamphetamine - chemistry ; Nicotiana - chemistry ; Pharmacology. Drug treatments ; Plants, Toxic ; Tobacco, tobacco smoking ; Toxicology</subject><ispartof>Journal of analytical toxicology, 1999-01, Vol.23 (1), p.41-45</ispartof><rights>1999</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c451t-ea421b017b1d74ee8bf91cafb5a069530f23dd8a7ceacc87f9824b53e2fe93d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1578,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1671202$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10022208$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Maw-Rong</creatorcontrib><creatorcontrib>Jeng, Jsuey</creatorcontrib><creatorcontrib>Hsiang, Wei-Shin</creatorcontrib><creatorcontrib>Hwang, Bao-Huey</creatorcontrib><title>Determination of Pyrolysis Products of Smoked Methamphetamine Mixed with Tobacco by Tandem Mass Spectrometry</title><title>Journal of analytical toxicology</title><addtitle>Journal of Analytical Toxicology</addtitle><addtitle>Journal of Analytical Toxicology</addtitle><description>This study examines the pyrolysis products of smoked methamphetamine mixed with tobacco that was trapped with a C8 adsorbent cartridge and then detected by gas chromatography-tandem mass spectrometry. According to the results, the mainstream smoke contains 2-methylpropyl-benzene, 2-chloropropyl-benzene, 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one, 3-ethyl-phenol, methamphetamine, dimethylamphetamine, hydroquinone, 3-methyl-5-(1-methylethyl)-methylcarbamate phenol, N-methyl-N-(2-phenylethyl)-acetamide, 4-(3-hydroxy-1-butenyl)-3,5,5-trimethyl-2-cyclohexene-1-one, propanoic acid, N-acetylmethamphetamine, phenyl ester, and furfurylmethylamphetamine. In addition, the compounds in sidestream smoke are 2-propenyl benzene, phenylacetone, methamphetamine, dimethylamphetamine, benzyl methyl ketoxime, 3,4-dihydro-2-naphthalenone, N-folmyamphetamine, N-acetylamphetamine, bibenzyl, N-folmylmethamphetamine, N-acetylmethamphetamine, N-propionymethamphetamine, and furfurylmethylamphetamine. Moreover, the presence of methamphetamine promotes the oxidation of the tobacco components.</description><subject>Analysis</subject><subject>Biological and medical sciences</subject><subject>Drug Interactions</subject><subject>Gas Chromatography-Mass Spectrometry</subject><subject>General pharmacology</subject><subject>Hot Temperature</subject><subject>Medical sciences</subject><subject>Methamphetamine - analysis</subject><subject>Methamphetamine - chemistry</subject><subject>Nicotiana - chemistry</subject><subject>Pharmacology. Drug treatments</subject><subject>Plants, Toxic</subject><subject>Tobacco, tobacco smoking</subject><subject>Toxicology</subject><issn>0146-4760</issn><issn>1945-2403</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0M-L1DAUB_AgijuunrxLDuJFOpuXpE17lNF1hR1cmEHES0jTF6a7bdNNUtz-93aZwfXm6cHj837wJeQtsDWwSlzcmnTBxRrWEp6RFVQyz7hk4jlZMZBFJlXBzsirGG8Zg6IsxEtyBoxxzlm5It1nTBj6djCp9QP1jt7MwXdzbCO9Cb6ZbIqP3V3v77ChW0wH048HTGaZQbptH5bu7zYd6N7XxlpP65nuzdBgT7cmRrob0abge0xhfk1eONNFfHOq52R_-WW_ucquv3_9tvl0nVmZQ8rQSA41A1VDoyRiWbsKrHF1blhR5YI5LpqmNMricrFUriq5rHOB3GElGnFOPhzXjsHfTxiT7ttosevMgH6KGhRneVXJBX48Qht8jAGdHkPbmzBrYPoxW71kq7nQoCUs-t1p7VT32Pxjj2Eu4P0JmGhN54IZbBufXKGAM_70np_G_xzMjrCNCR_-UhPudKGEyvXVz19aXFbsB-w2Woo_R2ufFQ</recordid><startdate>19990101</startdate><enddate>19990101</enddate><creator>Lee, Maw-Rong</creator><creator>Jeng, Jsuey</creator><creator>Hsiang, Wei-Shin</creator><creator>Hwang, Bao-Huey</creator><general>Oxford University Press</general><general>Preston</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>19990101</creationdate><title>Determination of Pyrolysis Products of Smoked Methamphetamine Mixed with Tobacco by Tandem Mass Spectrometry</title><author>Lee, Maw-Rong ; Jeng, Jsuey ; Hsiang, Wei-Shin ; Hwang, Bao-Huey</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c451t-ea421b017b1d74ee8bf91cafb5a069530f23dd8a7ceacc87f9824b53e2fe93d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Analysis</topic><topic>Biological and medical sciences</topic><topic>Drug Interactions</topic><topic>Gas Chromatography-Mass Spectrometry</topic><topic>General pharmacology</topic><topic>Hot Temperature</topic><topic>Medical sciences</topic><topic>Methamphetamine - analysis</topic><topic>Methamphetamine - chemistry</topic><topic>Nicotiana - chemistry</topic><topic>Pharmacology. Drug treatments</topic><topic>Plants, Toxic</topic><topic>Tobacco, tobacco smoking</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Maw-Rong</creatorcontrib><creatorcontrib>Jeng, Jsuey</creatorcontrib><creatorcontrib>Hsiang, Wei-Shin</creatorcontrib><creatorcontrib>Hwang, Bao-Huey</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Journal of analytical toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Maw-Rong</au><au>Jeng, Jsuey</au><au>Hsiang, Wei-Shin</au><au>Hwang, Bao-Huey</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Determination of Pyrolysis Products of Smoked Methamphetamine Mixed with Tobacco by Tandem Mass Spectrometry</atitle><jtitle>Journal of analytical toxicology</jtitle><stitle>Journal of Analytical Toxicology</stitle><addtitle>Journal of Analytical Toxicology</addtitle><date>1999-01-01</date><risdate>1999</risdate><volume>23</volume><issue>1</issue><spage>41</spage><epage>45</epage><pages>41-45</pages><issn>0146-4760</issn><eissn>1945-2403</eissn><coden>JATOD3</coden><abstract>This study examines the pyrolysis products of smoked methamphetamine mixed with tobacco that was trapped with a C8 adsorbent cartridge and then detected by gas chromatography-tandem mass spectrometry. According to the results, the mainstream smoke contains 2-methylpropyl-benzene, 2-chloropropyl-benzene, 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one, 3-ethyl-phenol, methamphetamine, dimethylamphetamine, hydroquinone, 3-methyl-5-(1-methylethyl)-methylcarbamate phenol, N-methyl-N-(2-phenylethyl)-acetamide, 4-(3-hydroxy-1-butenyl)-3,5,5-trimethyl-2-cyclohexene-1-one, propanoic acid, N-acetylmethamphetamine, phenyl ester, and furfurylmethylamphetamine. In addition, the compounds in sidestream smoke are 2-propenyl benzene, phenylacetone, methamphetamine, dimethylamphetamine, benzyl methyl ketoxime, 3,4-dihydro-2-naphthalenone, N-folmyamphetamine, N-acetylamphetamine, bibenzyl, N-folmylmethamphetamine, N-acetylmethamphetamine, N-propionymethamphetamine, and furfurylmethylamphetamine. Moreover, the presence of methamphetamine promotes the oxidation of the tobacco components.</abstract><cop>Niles, IL</cop><pub>Oxford University Press</pub><pmid>10022208</pmid><doi>10.1093/jat/23.1.41</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Analysis Biological and medical sciences Drug Interactions Gas Chromatography-Mass Spectrometry General pharmacology Hot Temperature Medical sciences Methamphetamine - analysis Methamphetamine - chemistry Nicotiana - chemistry Pharmacology. Drug treatments Plants, Toxic Tobacco, tobacco smoking Toxicology |
| title | Determination of Pyrolysis Products of Smoked Methamphetamine Mixed with Tobacco by Tandem Mass Spectrometry |
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