MUC1 is a novel marker for the type II pneumocyte lineage during lung carcinogenesis

Abnormalities in mucin-type glycoprotein expression have been documented in a variety of cancers, identifying these molecules as targets for immunologically based therapies and prognostic/diagnostic assays. We examined the expression of the membrane-bound MUC1 mucin in normal, histologically atypica...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1998-12, Vol.58 (23), p.5582-5589
Hauptverfasser:	JARRARD, J. A, LINNOILA, R. I, LEE, H, STEINBERG, S. M, WITSCHI, H, SZABO, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biomarkers, Tumor - biosynthesis Carcinogens Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - pathology Carcinoma, Non-Small-Cell Lung - secondary Cell Differentiation - physiology Cell Lineage Cricetinae Down-Regulation Female Histone Deacetylase Inhibitors Humans Immunohistochemistry Lung - metabolism Lung Neoplasms - metabolism Lung Neoplasms - pathology Lung Neoplasms - secondary Male Medical sciences Mesocricetus Middle Aged Mucin-1 Nitrosamines Oligopeptides - biosynthesis Peptide Fragments Pneumology Pulmonary Alveoli - cytology Pulmonary Alveoli - metabolism RNA, Messenger - metabolism Tumors of the respiratory system and mediastinum
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