Potential role of Clostridium difficile as a cause of duodenitis-proximal jejunitis in horses
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Canada, N1G 2WI Correspondence Luis G. Arroyo larroyo{at}uoguelph.ca Received 17 September 2005 Accepted 27 January 2006 Duodenitis-proximal jejunitis (DPJ) is an idiopathic condition in the horse characterized...
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| Veröffentlicht in: | Journal of medical microbiology 2006-05, Vol.55 (5), p.605-608 |
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| container_title | Journal of medical microbiology |
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| creator | Arroyo, Luis G Stampfli, Henry R Weese, J. Scott |
| description | Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Canada, N1G 2WI
Correspondence Luis G. Arroyo larroyo{at}uoguelph.ca
Received 17 September 2005
Accepted 27 January 2006
Duodenitis-proximal jejunitis (DPJ) is an idiopathic condition in the horse characterized by inflammation and oedema of the duodenum and proximal jejunum. Clinical signs include colic, ileus, depression, fluid accumulation in the small intestine and stomach, and endotoxaemia. The objective of this study was to investigate prospectively the role of Clostridium difficile in this idiopathic disease. Nasogastric reflux from 10 consecutive cases with DPJ and 16 consecutive horses with other causes of nasogastric reflux was cultured for C. difficile , other Clostridium spp., and Salmonella . Toxigenic strains of C. difficile were isolated from 10/10 (100 %) of horses with DPJ and 1/16 controls ( P |
| doi_str_mv | 10.1099/jmm.0.46334-0 |
| format | Article |
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Correspondence Luis G. Arroyo larroyo{at}uoguelph.ca
Received 17 September 2005
Accepted 27 January 2006
Duodenitis-proximal jejunitis (DPJ) is an idiopathic condition in the horse characterized by inflammation and oedema of the duodenum and proximal jejunum. Clinical signs include colic, ileus, depression, fluid accumulation in the small intestine and stomach, and endotoxaemia. The objective of this study was to investigate prospectively the role of Clostridium difficile in this idiopathic disease. Nasogastric reflux from 10 consecutive cases with DPJ and 16 consecutive horses with other causes of nasogastric reflux was cultured for C. difficile , other Clostridium spp., and Salmonella . Toxigenic strains of C. difficile were isolated from 10/10 (100 %) of horses with DPJ and 1/16 controls ( P <0·0001). No other known pathogenic clostridia were isolated from either group. Results of this study suggest that C. difficile might be an important cause of this syndrome.
Abbreviations: DPJ, duodenitis-proximal jejunitis.</description><identifier>ISSN: 0022-2615</identifier><identifier>EISSN: 1473-5644</identifier><identifier>DOI: 10.1099/jmm.0.46334-0</identifier><identifier>PMID: 16585649</identifier><identifier>CODEN: JMMIAV</identifier><language>eng</language><publisher>Reading: Soc General Microbiol</publisher><subject>Animals ; Biological and medical sciences ; Clostridium difficile ; Clostridium difficile - isolation & purification ; Clostridium difficile - pathogenicity ; Clostridium Infections - microbiology ; Clostridium Infections - veterinary ; Duodenitis - microbiology ; Duodenitis - veterinary ; Fundamental and applied biological sciences. Psychology ; Gastroesophageal Reflux - microbiology ; Horse Diseases - microbiology ; Horses ; Infectious diseases ; Jejunal Diseases - microbiology ; Jejunal Diseases - veterinary ; Medical sciences ; Microbiology ; Salmonella ; Salmonella - isolation & purification</subject><ispartof>Journal of medical microbiology, 2006-05, Vol.55 (5), p.605-608</ispartof><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c423t-3e7624233aee86bc74bf51b31c0465e8ec382c0c156748b02a9ec7f5340734223</citedby><cites>FETCH-LOGICAL-c423t-3e7624233aee86bc74bf51b31c0465e8ec382c0c156748b02a9ec7f5340734223</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3733,3734,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17709821$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16585649$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Arroyo, Luis G</creatorcontrib><creatorcontrib>Stampfli, Henry R</creatorcontrib><creatorcontrib>Weese, J. Scott</creatorcontrib><title>Potential role of Clostridium difficile as a cause of duodenitis-proximal jejunitis in horses</title><title>Journal of medical microbiology</title><addtitle>J Med Microbiol</addtitle><description>Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Canada, N1G 2WI
Correspondence Luis G. Arroyo larroyo{at}uoguelph.ca
Received 17 September 2005
Accepted 27 January 2006
Duodenitis-proximal jejunitis (DPJ) is an idiopathic condition in the horse characterized by inflammation and oedema of the duodenum and proximal jejunum. Clinical signs include colic, ileus, depression, fluid accumulation in the small intestine and stomach, and endotoxaemia. The objective of this study was to investigate prospectively the role of Clostridium difficile in this idiopathic disease. Nasogastric reflux from 10 consecutive cases with DPJ and 16 consecutive horses with other causes of nasogastric reflux was cultured for C. difficile , other Clostridium spp., and Salmonella . Toxigenic strains of C. difficile were isolated from 10/10 (100 %) of horses with DPJ and 1/16 controls ( P <0·0001). No other known pathogenic clostridia were isolated from either group. Results of this study suggest that C. difficile might be an important cause of this syndrome.
Abbreviations: DPJ, duodenitis-proximal jejunitis.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Clostridium difficile</subject><subject>Clostridium difficile - isolation & purification</subject><subject>Clostridium difficile - pathogenicity</subject><subject>Clostridium Infections - microbiology</subject><subject>Clostridium Infections - veterinary</subject><subject>Duodenitis - microbiology</subject><subject>Duodenitis - veterinary</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gastroesophageal Reflux - microbiology</subject><subject>Horse Diseases - microbiology</subject><subject>Horses</subject><subject>Infectious diseases</subject><subject>Jejunal Diseases - microbiology</subject><subject>Jejunal Diseases - veterinary</subject><subject>Medical sciences</subject><subject>Microbiology</subject><subject>Salmonella</subject><subject>Salmonella - isolation & purification</subject><issn>0022-2615</issn><issn>1473-5644</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0Etr3DAUBWARGpJJ2mW3xZs2K0-u3vayDH3BQLJIl0XI8nVGg22lkk2Sfx9lxjArCenT1eEQ8pnCmkJd3-6HYQ1roTgXJZyRFRWal1IJ8YGsABgrmaLyklyltAegmvP6glxSJats6hX5dx8mHCdv-yKGHovQFZs-pCn61s9D0fqu887nC5sKWzg7p4Np59Di6CefyqcYXvyQ3-9xPx-OCj8WuxATpo_kvLN9wk_Lek3-_vzxsPldbu9-_dl835ZOMD6VHLViecctYqUap0XTSdpw6kAoiRU6XjEHjkqlRdUAszU63UkuQHPBGL8m345zc5j_M6bJDD457Hs7YpiToZrWdUWrDMsjdDGkFLEzTzGHj6-Ggnnv0-Q-DZhDnway_7IMnpsB25NeCszg6wJscrbvoh2dTyenNdQVo9ndHN3OP-6efUTziOPgc4zGh_dPpTTSKJD8DUthjAs</recordid><startdate>20060501</startdate><enddate>20060501</enddate><creator>Arroyo, Luis G</creator><creator>Stampfli, Henry R</creator><creator>Weese, J. Scott</creator><general>Soc General Microbiol</general><general>Society for General Microbiology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope></search><sort><creationdate>20060501</creationdate><title>Potential role of Clostridium difficile as a cause of duodenitis-proximal jejunitis in horses</title><author>Arroyo, Luis G ; Stampfli, Henry R ; Weese, J. Scott</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-3e7624233aee86bc74bf51b31c0465e8ec382c0c156748b02a9ec7f5340734223</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Clostridium difficile</topic><topic>Clostridium difficile - isolation & purification</topic><topic>Clostridium difficile - pathogenicity</topic><topic>Clostridium Infections - microbiology</topic><topic>Clostridium Infections - veterinary</topic><topic>Duodenitis - microbiology</topic><topic>Duodenitis - veterinary</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gastroesophageal Reflux - microbiology</topic><topic>Horse Diseases - microbiology</topic><topic>Horses</topic><topic>Infectious diseases</topic><topic>Jejunal Diseases - microbiology</topic><topic>Jejunal Diseases - veterinary</topic><topic>Medical sciences</topic><topic>Microbiology</topic><topic>Salmonella</topic><topic>Salmonella - isolation & purification</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Arroyo, Luis G</creatorcontrib><creatorcontrib>Stampfli, Henry R</creatorcontrib><creatorcontrib>Weese, J. Scott</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Journal of medical microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Arroyo, Luis G</au><au>Stampfli, Henry R</au><au>Weese, J. Scott</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Potential role of Clostridium difficile as a cause of duodenitis-proximal jejunitis in horses</atitle><jtitle>Journal of medical microbiology</jtitle><addtitle>J Med Microbiol</addtitle><date>2006-05-01</date><risdate>2006</risdate><volume>55</volume><issue>5</issue><spage>605</spage><epage>608</epage><pages>605-608</pages><issn>0022-2615</issn><eissn>1473-5644</eissn><coden>JMMIAV</coden><abstract>Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Canada, N1G 2WI
Correspondence Luis G. Arroyo larroyo{at}uoguelph.ca
Received 17 September 2005
Accepted 27 January 2006
Duodenitis-proximal jejunitis (DPJ) is an idiopathic condition in the horse characterized by inflammation and oedema of the duodenum and proximal jejunum. Clinical signs include colic, ileus, depression, fluid accumulation in the small intestine and stomach, and endotoxaemia. The objective of this study was to investigate prospectively the role of Clostridium difficile in this idiopathic disease. Nasogastric reflux from 10 consecutive cases with DPJ and 16 consecutive horses with other causes of nasogastric reflux was cultured for C. difficile , other Clostridium spp., and Salmonella . Toxigenic strains of C. difficile were isolated from 10/10 (100 %) of horses with DPJ and 1/16 controls ( P <0·0001). No other known pathogenic clostridia were isolated from either group. Results of this study suggest that C. difficile might be an important cause of this syndrome.
Abbreviations: DPJ, duodenitis-proximal jejunitis.</abstract><cop>Reading</cop><pub>Soc General Microbiol</pub><pmid>16585649</pmid><doi>10.1099/jmm.0.46334-0</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Microbiology Society; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Animals Biological and medical sciences Clostridium difficile Clostridium difficile - isolation & purification Clostridium difficile - pathogenicity Clostridium Infections - microbiology Clostridium Infections - veterinary Duodenitis - microbiology Duodenitis - veterinary Fundamental and applied biological sciences. Psychology Gastroesophageal Reflux - microbiology Horse Diseases - microbiology Horses Infectious diseases Jejunal Diseases - microbiology Jejunal Diseases - veterinary Medical sciences Microbiology Salmonella Salmonella - isolation & purification |
| title | Potential role of Clostridium difficile as a cause of duodenitis-proximal jejunitis in horses |
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