Identification of single nucleotide polymorphisms in the ASB15 gene and their associations with chicken growth and carcass traits
ASB15 is a member of the ankyrin repeat and suppressor of cytokine signaling box family, and is predominantly expressed in skeletal muscle. In the present study, an F2 resource population of Gushi chickens crossed with Anka broilers was used to investigate the genetic effects of the chicken ASB15 ge...
Gespeichert in:
| Veröffentlicht in: | Genetics and molecular research 2015-09, Vol.14 (3), p.11377-11388 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 11388 |
|---|---|
| container_issue | 3 |
| container_start_page | 11377 |
| container_title | Genetics and molecular research |
| container_volume | 14 |
| creator | Wang, Y C Jiang, R R Kang, X T Li, Z J Han, R L Geng, J Fu, J X Wang, J F Wu, J P |
| description | ASB15 is a member of the ankyrin repeat and suppressor of cytokine signaling box family, and is predominantly expressed in skeletal muscle. In the present study, an F2 resource population of Gushi chickens crossed with Anka broilers was used to investigate the genetic effects of the chicken ASB15 gene. Two single nucleotide polymorphisms (SNPs) (rs315759231 A>G and rs312619270 T>C) were identified in exon 7 of the ASB15 gene using forced chain reaction-restriction fragment length polymorphism and DNA sequencing. One was a missense SNP (rs315759231 A>G) and the other was a synonymous SNP (rs312619270 T>C). The rs315759231 A>G polymorphism was significantly associated with body weight at birth, 12-week body slanting length, semi-evisceration weight, evisceration weight, leg muscle weight, and carcass weight (P < 0.05). The rs312619270 T>C polymorphism was significantly associated with body weight at birth, 4, 8, and 12-week body weight, 8-week shank length, 12-week breast bone length, 8 and 12-week body slanting length, breast muscle weight, and carcass weight (P < 0.05). Our results suggest that the ASB15 gene profoundly affects chicken growth and carcass traits. |
| doi_str_mv | 10.4238/2015.September.25.5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1719974967</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1719974967</sourcerecordid><originalsourceid>FETCH-LOGICAL-c350t-56d56e9040d717aed8d68b3efbd397643c087e980ba2b5c4da6d6363bd9c7c5e3</originalsourceid><addsrcrecordid>eNpNkElPwzAQhS0EomX5BUjIRy4tThzbybFUbFIlDsDZcuxJa0jsYLuqeuSfk7JUnGbRezN6H0IXGZkWOS2vc5Kx6TP0CboawjRnU3aAxhkXfMJ4SQ7_9SN0EuMbITkrSnKMRjkvKKeiGqPPRwMu2cZqlax32Dc4WrdsAbu1bsEnawD3vt12PvQrG7uIrcNpBXj2fJMxvAQHWDmzW9mAVYxe2-9TEW9sWmG9svodHF4GvxnGnVSroAchTkHZFM_QUaPaCOe_9RS93t2-zB8mi6f7x_lsMdGUkTTEMIxDRQpiRCYUmNLwsqbQ1IZWYsijSSmgKkmt8prpwihu-BCyNpUWmgE9RVc_d_vgP9YQk-xs1NC2yoFfR5mJrKpEUXExSOmPVAcfY4BG9sF2KmxlRuSOvdyxl3v2MmeSDa7L3wfrugOz9_zBpl8P8oU0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1719974967</pqid></control><display><type>article</type><title>Identification of single nucleotide polymorphisms in the ASB15 gene and their associations with chicken growth and carcass traits</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Wang, Y C ; Jiang, R R ; Kang, X T ; Li, Z J ; Han, R L ; Geng, J ; Fu, J X ; Wang, J F ; Wu, J P</creator><creatorcontrib>Wang, Y C ; Jiang, R R ; Kang, X T ; Li, Z J ; Han, R L ; Geng, J ; Fu, J X ; Wang, J F ; Wu, J P</creatorcontrib><description>ASB15 is a member of the ankyrin repeat and suppressor of cytokine signaling box family, and is predominantly expressed in skeletal muscle. In the present study, an F2 resource population of Gushi chickens crossed with Anka broilers was used to investigate the genetic effects of the chicken ASB15 gene. Two single nucleotide polymorphisms (SNPs) (rs315759231 A>G and rs312619270 T>C) were identified in exon 7 of the ASB15 gene using forced chain reaction-restriction fragment length polymorphism and DNA sequencing. One was a missense SNP (rs315759231 A>G) and the other was a synonymous SNP (rs312619270 T>C). The rs315759231 A>G polymorphism was significantly associated with body weight at birth, 12-week body slanting length, semi-evisceration weight, evisceration weight, leg muscle weight, and carcass weight (P < 0.05). The rs312619270 T>C polymorphism was significantly associated with body weight at birth, 4, 8, and 12-week body weight, 8-week shank length, 12-week breast bone length, 8 and 12-week body slanting length, breast muscle weight, and carcass weight (P < 0.05). Our results suggest that the ASB15 gene profoundly affects chicken growth and carcass traits.</description><identifier>ISSN: 1676-5680</identifier><identifier>EISSN: 1676-5680</identifier><identifier>DOI: 10.4238/2015.September.25.5</identifier><identifier>PMID: 26436379</identifier><language>eng</language><publisher>Brazil</publisher><subject>Animals ; Avian Proteins - genetics ; Base Sequence ; Chickens - genetics ; Chickens - growth & development ; Electrophoresis, Agar Gel ; Female ; Gene Frequency - genetics ; Genetic Association Studies ; Genotyping Techniques ; Linkage Disequilibrium - genetics ; Male ; Meat ; Molecular Sequence Data ; Polymorphism, Restriction Fragment Length ; Polymorphism, Single Nucleotide - genetics ; Quantitative Trait, Heritable ; Sequence Analysis, DNA</subject><ispartof>Genetics and molecular research, 2015-09, Vol.14 (3), p.11377-11388</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c350t-56d56e9040d717aed8d68b3efbd397643c087e980ba2b5c4da6d6363bd9c7c5e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26436379$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Y C</creatorcontrib><creatorcontrib>Jiang, R R</creatorcontrib><creatorcontrib>Kang, X T</creatorcontrib><creatorcontrib>Li, Z J</creatorcontrib><creatorcontrib>Han, R L</creatorcontrib><creatorcontrib>Geng, J</creatorcontrib><creatorcontrib>Fu, J X</creatorcontrib><creatorcontrib>Wang, J F</creatorcontrib><creatorcontrib>Wu, J P</creatorcontrib><title>Identification of single nucleotide polymorphisms in the ASB15 gene and their associations with chicken growth and carcass traits</title><title>Genetics and molecular research</title><addtitle>Genet Mol Res</addtitle><description>ASB15 is a member of the ankyrin repeat and suppressor of cytokine signaling box family, and is predominantly expressed in skeletal muscle. In the present study, an F2 resource population of Gushi chickens crossed with Anka broilers was used to investigate the genetic effects of the chicken ASB15 gene. Two single nucleotide polymorphisms (SNPs) (rs315759231 A>G and rs312619270 T>C) were identified in exon 7 of the ASB15 gene using forced chain reaction-restriction fragment length polymorphism and DNA sequencing. One was a missense SNP (rs315759231 A>G) and the other was a synonymous SNP (rs312619270 T>C). The rs315759231 A>G polymorphism was significantly associated with body weight at birth, 12-week body slanting length, semi-evisceration weight, evisceration weight, leg muscle weight, and carcass weight (P < 0.05). The rs312619270 T>C polymorphism was significantly associated with body weight at birth, 4, 8, and 12-week body weight, 8-week shank length, 12-week breast bone length, 8 and 12-week body slanting length, breast muscle weight, and carcass weight (P < 0.05). Our results suggest that the ASB15 gene profoundly affects chicken growth and carcass traits.</description><subject>Animals</subject><subject>Avian Proteins - genetics</subject><subject>Base Sequence</subject><subject>Chickens - genetics</subject><subject>Chickens - growth & development</subject><subject>Electrophoresis, Agar Gel</subject><subject>Female</subject><subject>Gene Frequency - genetics</subject><subject>Genetic Association Studies</subject><subject>Genotyping Techniques</subject><subject>Linkage Disequilibrium - genetics</subject><subject>Male</subject><subject>Meat</subject><subject>Molecular Sequence Data</subject><subject>Polymorphism, Restriction Fragment Length</subject><subject>Polymorphism, Single Nucleotide - genetics</subject><subject>Quantitative Trait, Heritable</subject><subject>Sequence Analysis, DNA</subject><issn>1676-5680</issn><issn>1676-5680</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkElPwzAQhS0EomX5BUjIRy4tThzbybFUbFIlDsDZcuxJa0jsYLuqeuSfk7JUnGbRezN6H0IXGZkWOS2vc5Kx6TP0CboawjRnU3aAxhkXfMJ4SQ7_9SN0EuMbITkrSnKMRjkvKKeiGqPPRwMu2cZqlax32Dc4WrdsAbu1bsEnawD3vt12PvQrG7uIrcNpBXj2fJMxvAQHWDmzW9mAVYxe2-9TEW9sWmG9svodHF4GvxnGnVSroAchTkHZFM_QUaPaCOe_9RS93t2-zB8mi6f7x_lsMdGUkTTEMIxDRQpiRCYUmNLwsqbQ1IZWYsijSSmgKkmt8prpwihu-BCyNpUWmgE9RVc_d_vgP9YQk-xs1NC2yoFfR5mJrKpEUXExSOmPVAcfY4BG9sF2KmxlRuSOvdyxl3v2MmeSDa7L3wfrugOz9_zBpl8P8oU0</recordid><startdate>20150925</startdate><enddate>20150925</enddate><creator>Wang, Y C</creator><creator>Jiang, R R</creator><creator>Kang, X T</creator><creator>Li, Z J</creator><creator>Han, R L</creator><creator>Geng, J</creator><creator>Fu, J X</creator><creator>Wang, J F</creator><creator>Wu, J P</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150925</creationdate><title>Identification of single nucleotide polymorphisms in the ASB15 gene and their associations with chicken growth and carcass traits</title><author>Wang, Y C ; Jiang, R R ; Kang, X T ; Li, Z J ; Han, R L ; Geng, J ; Fu, J X ; Wang, J F ; Wu, J P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c350t-56d56e9040d717aed8d68b3efbd397643c087e980ba2b5c4da6d6363bd9c7c5e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Animals</topic><topic>Avian Proteins - genetics</topic><topic>Base Sequence</topic><topic>Chickens - genetics</topic><topic>Chickens - growth & development</topic><topic>Electrophoresis, Agar Gel</topic><topic>Female</topic><topic>Gene Frequency - genetics</topic><topic>Genetic Association Studies</topic><topic>Genotyping Techniques</topic><topic>Linkage Disequilibrium - genetics</topic><topic>Male</topic><topic>Meat</topic><topic>Molecular Sequence Data</topic><topic>Polymorphism, Restriction Fragment Length</topic><topic>Polymorphism, Single Nucleotide - genetics</topic><topic>Quantitative Trait, Heritable</topic><topic>Sequence Analysis, DNA</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Y C</creatorcontrib><creatorcontrib>Jiang, R R</creatorcontrib><creatorcontrib>Kang, X T</creatorcontrib><creatorcontrib>Li, Z J</creatorcontrib><creatorcontrib>Han, R L</creatorcontrib><creatorcontrib>Geng, J</creatorcontrib><creatorcontrib>Fu, J X</creatorcontrib><creatorcontrib>Wang, J F</creatorcontrib><creatorcontrib>Wu, J P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Genetics and molecular research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Y C</au><au>Jiang, R R</au><au>Kang, X T</au><au>Li, Z J</au><au>Han, R L</au><au>Geng, J</au><au>Fu, J X</au><au>Wang, J F</au><au>Wu, J P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification of single nucleotide polymorphisms in the ASB15 gene and their associations with chicken growth and carcass traits</atitle><jtitle>Genetics and molecular research</jtitle><addtitle>Genet Mol Res</addtitle><date>2015-09-25</date><risdate>2015</risdate><volume>14</volume><issue>3</issue><spage>11377</spage><epage>11388</epage><pages>11377-11388</pages><issn>1676-5680</issn><eissn>1676-5680</eissn><abstract>ASB15 is a member of the ankyrin repeat and suppressor of cytokine signaling box family, and is predominantly expressed in skeletal muscle. In the present study, an F2 resource population of Gushi chickens crossed with Anka broilers was used to investigate the genetic effects of the chicken ASB15 gene. Two single nucleotide polymorphisms (SNPs) (rs315759231 A>G and rs312619270 T>C) were identified in exon 7 of the ASB15 gene using forced chain reaction-restriction fragment length polymorphism and DNA sequencing. One was a missense SNP (rs315759231 A>G) and the other was a synonymous SNP (rs312619270 T>C). The rs315759231 A>G polymorphism was significantly associated with body weight at birth, 12-week body slanting length, semi-evisceration weight, evisceration weight, leg muscle weight, and carcass weight (P < 0.05). The rs312619270 T>C polymorphism was significantly associated with body weight at birth, 4, 8, and 12-week body weight, 8-week shank length, 12-week breast bone length, 8 and 12-week body slanting length, breast muscle weight, and carcass weight (P < 0.05). Our results suggest that the ASB15 gene profoundly affects chicken growth and carcass traits.</abstract><cop>Brazil</cop><pmid>26436379</pmid><doi>10.4238/2015.September.25.5</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1676-5680 |
| ispartof | Genetics and molecular research, 2015-09, Vol.14 (3), p.11377-11388 |
| issn | 1676-5680 1676-5680 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1719974967 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Animals Avian Proteins - genetics Base Sequence Chickens - genetics Chickens - growth & development Electrophoresis, Agar Gel Female Gene Frequency - genetics Genetic Association Studies Genotyping Techniques Linkage Disequilibrium - genetics Male Meat Molecular Sequence Data Polymorphism, Restriction Fragment Length Polymorphism, Single Nucleotide - genetics Quantitative Trait, Heritable Sequence Analysis, DNA |
| title | Identification of single nucleotide polymorphisms in the ASB15 gene and their associations with chicken growth and carcass traits |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T18%3A25%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Identification%20of%20single%20nucleotide%20polymorphisms%20in%20the%20ASB15%20gene%20and%20their%20associations%20with%20chicken%20growth%20and%20carcass%20traits&rft.jtitle=Genetics%20and%20molecular%20research&rft.au=Wang,%20Y%20C&rft.date=2015-09-25&rft.volume=14&rft.issue=3&rft.spage=11377&rft.epage=11388&rft.pages=11377-11388&rft.issn=1676-5680&rft.eissn=1676-5680&rft_id=info:doi/10.4238/2015.September.25.5&rft_dat=%3Cproquest_cross%3E1719974967%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1719974967&rft_id=info:pmid/26436379&rfr_iscdi=true |