High Mobility Group-I(Y) Protein Facilitates Nuclear Factor-κB Binding and Transactivation of the Inducible Nitric-oxide Synthase Promoter/Enhancer

Nitric oxide (NO), a free radical gas whose production is catalyzed by the enzyme NO synthase, participates in the regulation of multiple organ systems. The inducible isoform of NO synthase (iNOS) is transcriptionally up-regulated by inflammatory stimuli; a critical mediator of this process is nucle...

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Veröffentlicht in:The Journal of biological chemistry 1999-03, Vol.274 (13), p.9045-9052
Hauptverfasser: Perrella, Mark A., Pellacani, Andrea, Wiesel, Philippe, Chin, Michael T., Foster, Lauren C., Ibanez, Maureen, Hsieh, Chung-Ming, Reeves, Raymond, Yet, Shaw-Fang, Lee, Mu-En
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Sprache:eng
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