Maxillary Sinus Augmentation with a New Xenograft: A Randomized Controlled Clinical Trial

Background Insufficient residual alveolar bone height is a common deterrent in the placement of dental implants in the posterior maxilla. The use of autografts, xenografts, allografts and alloplasts or a combination between them has been demonstrated to be effective for increasing bone height and bo...

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Veröffentlicht in:Clinical implant dentistry and related research 2015-10, Vol.17 (S2), p.e586-e593
Hauptverfasser: Calasans-Maia, Mônica Diuana, Mourão, Carlos Fernando de A. B., Alves, Adriana Terezinha Neves Novellino, Sartoretto, Suelen Cristina, de Uzeda, Marcelo José P. G., Granjeiro, José Mauro
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container_issue S2
container_start_page e586
container_title Clinical implant dentistry and related research
container_volume 17
creator Calasans-Maia, Mônica Diuana
Mourão, Carlos Fernando de A. B.
Alves, Adriana Terezinha Neves Novellino
Sartoretto, Suelen Cristina
de Uzeda, Marcelo José P. G.
Granjeiro, José Mauro
description Background Insufficient residual alveolar bone height is a common deterrent in the placement of dental implants in the posterior maxilla. The use of autografts, xenografts, allografts and alloplasts or a combination between them has been demonstrated to be effective for increasing bone height and bone volume in the deficient posterior maxilla. Purpose The aim of this clinical trial is to comparatively determine the density of newly formed in sinus floor augmentation bone after a 24‐week healing period treatment with a new bovine xenograft. Materials and Methods The sinus floor was grafted with Bio‐Oss® (n = 10) and Osseous® (n = 10). Histological sections were examined with a focus on the presence of connective tissue (CT) and newly formed bone (NFB). The sections were histomorphometrically evaluated and the definitive crown was inserted after 3 months. Results After 6 months, the mean value of new bone formation was 24.60 (±2.503), the CT was 42.60 (±4.006) and the remaining biomaterial was 25.40 (±2.547) in Bio‐Oss group. In Osseous group, the mean value of new bone formation was 24.90 (±3.542), the CT was 45.70 (±7.040) and the remaining biomaterial was 22.90 (±3.247). Conclusions Both biomaterials afforded a favorable implant position and the prosthetic rehabilitation.
doi_str_mv 10.1111/cid.12289
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B. ; Alves, Adriana Terezinha Neves Novellino ; Sartoretto, Suelen Cristina ; de Uzeda, Marcelo José P. G. ; Granjeiro, José Mauro</creator><creatorcontrib>Calasans-Maia, Mônica Diuana ; Mourão, Carlos Fernando de A. B. ; Alves, Adriana Terezinha Neves Novellino ; Sartoretto, Suelen Cristina ; de Uzeda, Marcelo José P. G. ; Granjeiro, José Mauro</creatorcontrib><description>Background Insufficient residual alveolar bone height is a common deterrent in the placement of dental implants in the posterior maxilla. The use of autografts, xenografts, allografts and alloplasts or a combination between them has been demonstrated to be effective for increasing bone height and bone volume in the deficient posterior maxilla. Purpose The aim of this clinical trial is to comparatively determine the density of newly formed in sinus floor augmentation bone after a 24‐week healing period treatment with a new bovine xenograft. Materials and Methods The sinus floor was grafted with Bio‐Oss® (n = 10) and Osseous® (n = 10). Histological sections were examined with a focus on the presence of connective tissue (CT) and newly formed bone (NFB). The sections were histomorphometrically evaluated and the definitive crown was inserted after 3 months. Results After 6 months, the mean value of new bone formation was 24.60 (±2.503), the CT was 42.60 (±4.006) and the remaining biomaterial was 25.40 (±2.547) in Bio‐Oss group. In Osseous group, the mean value of new bone formation was 24.90 (±3.542), the CT was 45.70 (±7.040) and the remaining biomaterial was 22.90 (±3.247). Conclusions Both biomaterials afforded a favorable implant position and the prosthetic rehabilitation.</description><identifier>ISSN: 1523-0899</identifier><identifier>EISSN: 1708-8208</identifier><identifier>DOI: 10.1111/cid.12289</identifier><identifier>PMID: 25535980</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Adult ; Aged ; Animals ; atrophic maxilla ; bone augmentation ; Bone Substitutes - therapeutic use ; Cattle ; Dental Implantation, Endosseous - methods ; Dentistry ; Female ; Heterografts - surgery ; Humans ; Male ; Middle Aged ; Minerals - therapeutic use ; Sinus Floor Augmentation - methods ; sinus floor elevation ; xenograft</subject><ispartof>Clinical implant dentistry and related research, 2015-10, Vol.17 (S2), p.e586-e593</ispartof><rights>2014 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3639-603035bdd892993202b76e9e7554941786c6ec0bd2468ddd6d95e75b501ef9113</citedby><cites>FETCH-LOGICAL-c3639-603035bdd892993202b76e9e7554941786c6ec0bd2468ddd6d95e75b501ef9113</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fcid.12289$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fcid.12289$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25535980$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Calasans-Maia, Mônica Diuana</creatorcontrib><creatorcontrib>Mourão, Carlos Fernando de A. B.</creatorcontrib><creatorcontrib>Alves, Adriana Terezinha Neves Novellino</creatorcontrib><creatorcontrib>Sartoretto, Suelen Cristina</creatorcontrib><creatorcontrib>de Uzeda, Marcelo José P. G.</creatorcontrib><creatorcontrib>Granjeiro, José Mauro</creatorcontrib><title>Maxillary Sinus Augmentation with a New Xenograft: A Randomized Controlled Clinical Trial</title><title>Clinical implant dentistry and related research</title><addtitle>Clinical Implant Dentistry and Related Research</addtitle><description>Background Insufficient residual alveolar bone height is a common deterrent in the placement of dental implants in the posterior maxilla. The use of autografts, xenografts, allografts and alloplasts or a combination between them has been demonstrated to be effective for increasing bone height and bone volume in the deficient posterior maxilla. Purpose The aim of this clinical trial is to comparatively determine the density of newly formed in sinus floor augmentation bone after a 24‐week healing period treatment with a new bovine xenograft. Materials and Methods The sinus floor was grafted with Bio‐Oss® (n = 10) and Osseous® (n = 10). Histological sections were examined with a focus on the presence of connective tissue (CT) and newly formed bone (NFB). The sections were histomorphometrically evaluated and the definitive crown was inserted after 3 months. Results After 6 months, the mean value of new bone formation was 24.60 (±2.503), the CT was 42.60 (±4.006) and the remaining biomaterial was 25.40 (±2.547) in Bio‐Oss group. In Osseous group, the mean value of new bone formation was 24.90 (±3.542), the CT was 45.70 (±7.040) and the remaining biomaterial was 22.90 (±3.247). Conclusions Both biomaterials afforded a favorable implant position and the prosthetic rehabilitation.</description><subject>Adult</subject><subject>Aged</subject><subject>Animals</subject><subject>atrophic maxilla</subject><subject>bone augmentation</subject><subject>Bone Substitutes - therapeutic use</subject><subject>Cattle</subject><subject>Dental Implantation, Endosseous - methods</subject><subject>Dentistry</subject><subject>Female</subject><subject>Heterografts - surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Minerals - therapeutic use</subject><subject>Sinus Floor Augmentation - methods</subject><subject>sinus floor elevation</subject><subject>xenograft</subject><issn>1523-0899</issn><issn>1708-8208</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kEtPGzEUha2KqkDoon8AeUkXQ_wYv9hFoYRIhEo0VenK8owdcOuZCfaMAvz6Og2w427ule53jnQOAF8wOsV5xrW3p5gQqT6AAyyQLCRBci_fjNACSaX2wWFKfxAiGHP8CewTxihTEh2A3wvz6EMw8Qn-8O2Q4GS4a1zbm953Ldz4_h4aeO028Na13V00q_4MTuCNaW3X-Gdn4bRr-9iFsD2Db31tAlxGb8IR-LgyIbnPL3sEfl58W04vi6vvs_l0clXUlFNVcEQRZZW1UhGlKEGkEtwpJxgrVYmF5DV3NaosKbm01nKrWH5WDGG3UhjTETjZ-a5j9zC41OvGp9rlTK3rhqSxwKokuBQko193aB27lKJb6XX0Tc6uMdLbJnVuUv9vMrPHL7ZD1Tj7Rr5Wl4HxDtj44J7ed9LT-fmrZbFT-NS7xzeFiX81F1Qw_et6ppcCLWbq9lwv6D-2xorB</recordid><startdate>201510</startdate><enddate>201510</enddate><creator>Calasans-Maia, Mônica Diuana</creator><creator>Mourão, Carlos Fernando de A. B.</creator><creator>Alves, Adriana Terezinha Neves Novellino</creator><creator>Sartoretto, Suelen Cristina</creator><creator>de Uzeda, Marcelo José P. G.</creator><creator>Granjeiro, José Mauro</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201510</creationdate><title>Maxillary Sinus Augmentation with a New Xenograft: A Randomized Controlled Clinical Trial</title><author>Calasans-Maia, Mônica Diuana ; Mourão, Carlos Fernando de A. B. ; Alves, Adriana Terezinha Neves Novellino ; Sartoretto, Suelen Cristina ; de Uzeda, Marcelo José P. G. ; Granjeiro, José Mauro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3639-603035bdd892993202b76e9e7554941786c6ec0bd2468ddd6d95e75b501ef9113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Animals</topic><topic>atrophic maxilla</topic><topic>bone augmentation</topic><topic>Bone Substitutes - therapeutic use</topic><topic>Cattle</topic><topic>Dental Implantation, Endosseous - methods</topic><topic>Dentistry</topic><topic>Female</topic><topic>Heterografts - surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Minerals - therapeutic use</topic><topic>Sinus Floor Augmentation - methods</topic><topic>sinus floor elevation</topic><topic>xenograft</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Calasans-Maia, Mônica Diuana</creatorcontrib><creatorcontrib>Mourão, Carlos Fernando de A. B.</creatorcontrib><creatorcontrib>Alves, Adriana Terezinha Neves Novellino</creatorcontrib><creatorcontrib>Sartoretto, Suelen Cristina</creatorcontrib><creatorcontrib>de Uzeda, Marcelo José P. G.</creatorcontrib><creatorcontrib>Granjeiro, José Mauro</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical implant dentistry and related research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Calasans-Maia, Mônica Diuana</au><au>Mourão, Carlos Fernando de A. B.</au><au>Alves, Adriana Terezinha Neves Novellino</au><au>Sartoretto, Suelen Cristina</au><au>de Uzeda, Marcelo José P. G.</au><au>Granjeiro, José Mauro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Maxillary Sinus Augmentation with a New Xenograft: A Randomized Controlled Clinical Trial</atitle><jtitle>Clinical implant dentistry and related research</jtitle><addtitle>Clinical Implant Dentistry and Related Research</addtitle><date>2015-10</date><risdate>2015</risdate><volume>17</volume><issue>S2</issue><spage>e586</spage><epage>e593</epage><pages>e586-e593</pages><issn>1523-0899</issn><eissn>1708-8208</eissn><abstract>Background Insufficient residual alveolar bone height is a common deterrent in the placement of dental implants in the posterior maxilla. The use of autografts, xenografts, allografts and alloplasts or a combination between them has been demonstrated to be effective for increasing bone height and bone volume in the deficient posterior maxilla. Purpose The aim of this clinical trial is to comparatively determine the density of newly formed in sinus floor augmentation bone after a 24‐week healing period treatment with a new bovine xenograft. Materials and Methods The sinus floor was grafted with Bio‐Oss® (n = 10) and Osseous® (n = 10). Histological sections were examined with a focus on the presence of connective tissue (CT) and newly formed bone (NFB). The sections were histomorphometrically evaluated and the definitive crown was inserted after 3 months. Results After 6 months, the mean value of new bone formation was 24.60 (±2.503), the CT was 42.60 (±4.006) and the remaining biomaterial was 25.40 (±2.547) in Bio‐Oss group. In Osseous group, the mean value of new bone formation was 24.90 (±3.542), the CT was 45.70 (±7.040) and the remaining biomaterial was 22.90 (±3.247). Conclusions Both biomaterials afforded a favorable implant position and the prosthetic rehabilitation.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>25535980</pmid><doi>10.1111/cid.12289</doi><tpages>8</tpages></addata></record>
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1708-8208
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source MEDLINE; Wiley Online Library All Journals
subjects Adult
Aged
Animals
atrophic maxilla
bone augmentation
Bone Substitutes - therapeutic use
Cattle
Dental Implantation, Endosseous - methods
Dentistry
Female
Heterografts - surgery
Humans
Male
Middle Aged
Minerals - therapeutic use
Sinus Floor Augmentation - methods
sinus floor elevation
xenograft
title Maxillary Sinus Augmentation with a New Xenograft: A Randomized Controlled Clinical Trial
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