Increased risk of cardiovascular events with parecoxib/valdecoxib : a systematic review and meta-analysis
Determines the risk of serious cardiovascular events associated with the use of the COX-2 inhibitor valdecoxib and its prodrug parecoxib following major surgery. Performs a systematic review and meta-analysis of placebo-controlled randomised double-blind clinical trials of IV parecoxib followed by o...
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Veröffentlicht in: | New Zealand medical journal 2005-11, Vol.118 (1226), p.10p |
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description | Determines the risk of serious cardiovascular events associated with the use of the COX-2 inhibitor valdecoxib and its prodrug parecoxib following major surgery. Performs a systematic review and meta-analysis of placebo-controlled randomised double-blind clinical trials of IV parecoxib followed by oral valdecoxib treatment, that presented data on serious cardiovascular events. Calculates the pooled fixed-effects estimates for the odds ratio for risk of cardiovascular events for the use of parecoxib/valdecoxib. Source: National Library of New Zealand Te Puna Matauranga o Aotearoa, licensed by the Department of Internal Affairs for re-use under the Creative Commons Attribution 3.0 New Zealand Licence. |
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language | eng |
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source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
subjects | Cardiovascular disease Clinical trials Diseases Drug therapy Drugs Heart Heart attacks Medicine Studies Surgery |
title | Increased risk of cardiovascular events with parecoxib/valdecoxib : a systematic review and meta-analysis |
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