Interface for Online Coupling of Surface Plasmon Resonance to Direct Analysis in Real Time Mass Spectrometry
The online coupling of surface plasmon resonance (SPR) with mass spectrometry (MS) has been highly desired for the complementary information provided by each of the two techniques. In this work, a novel interface for direct and online coupling of SPR to direct analysis in real time (DART) MS was dev...
Gespeichert in:
Veröffentlicht in: | Analytical chemistry (Washington) 2015-07, Vol.87 (13), p.6505-6509 |
---|---|
Hauptverfasser: | , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 6509 |
---|---|
container_issue | 13 |
container_start_page | 6505 |
container_title | Analytical chemistry (Washington) |
container_volume | 87 |
creator | Zhang, Yiding Li, Xianjiang Nie, Honggang Yang, Li Li, Ze Bai, Yu Niu, Li Song, Daqian Liu, Huwei |
description | The online coupling of surface plasmon resonance (SPR) with mass spectrometry (MS) has been highly desired for the complementary information provided by each of the two techniques. In this work, a novel interface for direct and online coupling of SPR to direct analysis in real time (DART) MS was developed. A spray tip connected with the outlet of the SPR flow solution was conducted as the sampling part of the DART-MS, with which the online coupling interface of SPR-MS was realized. Four model samples, acetaminophen, metronidazole, quinine, and hippuric acid, dissolved in three kinds of common buffers were used in the SPR-DART-MS experiments for performance evaluation of the interface and the optimization of DART conditions. The results showed consistent signal changes and high tolerance of nonvolatile salts of this SPR-MS system, demonstrating the feasibility of the interface for online coupling of SPR with MS and the potential application in the characterization of interaction under physiological conditions. |
doi_str_mv | 10.1021/acs.analchem.5b01272 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1718960626</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1694962361</sourcerecordid><originalsourceid>FETCH-LOGICAL-a409t-a87d99b11115187bc6bc43079d6cb7c3d0d110507d506a87fd464da6371f8fb43</originalsourceid><addsrcrecordid>eNqFkV1PwyAUhonRuPnxD4wh8cabzgNtob1c5teSmRk3rxtKqXahZUJ7sX8vs5smXig3EM7zvpzDi9AFgREBSm6EdCPRCC3fVT2KcyCU0wM0JDGFgCUJPURDAAgDygEG6MS5FQAhQNgxGlAGjIcRDJGeNq2ypZAKl8bieaOrRuGJ6db-8IZNiRddX37WwtWmwS_KmUY0_qY1-LaySrZ47PvYuMrhalsXGi-rWuEn4RxerD1gTa1auzlDR6XQTp3v9lP0en-3nDwGs_nDdDKeBSKCtA1Ewos0zYlfMUl4LlkuoxB4WjCZcxkWUPhBYuBFDMzDZRGxqBAs5KRMyjwKT9F177u25qNTrs3qykmltWiU6VxGOElS_wWU_Y-yNEoZDRnx6NUvdGU66yf_omKegO_JU1FPSWucs6rM1raqhd1kBLJtcJkPLtsHl-2C87LLnXmX16r4Fu2T8gD0wFb-8_Bfnp_5Y6Yo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1695780050</pqid></control><display><type>article</type><title>Interface for Online Coupling of Surface Plasmon Resonance to Direct Analysis in Real Time Mass Spectrometry</title><source>ACS Publications</source><source>MEDLINE</source><creator>Zhang, Yiding ; Li, Xianjiang ; Nie, Honggang ; Yang, Li ; Li, Ze ; Bai, Yu ; Niu, Li ; Song, Daqian ; Liu, Huwei</creator><creatorcontrib>Zhang, Yiding ; Li, Xianjiang ; Nie, Honggang ; Yang, Li ; Li, Ze ; Bai, Yu ; Niu, Li ; Song, Daqian ; Liu, Huwei</creatorcontrib><description>The online coupling of surface plasmon resonance (SPR) with mass spectrometry (MS) has been highly desired for the complementary information provided by each of the two techniques. In this work, a novel interface for direct and online coupling of SPR to direct analysis in real time (DART) MS was developed. A spray tip connected with the outlet of the SPR flow solution was conducted as the sampling part of the DART-MS, with which the online coupling interface of SPR-MS was realized. Four model samples, acetaminophen, metronidazole, quinine, and hippuric acid, dissolved in three kinds of common buffers were used in the SPR-DART-MS experiments for performance evaluation of the interface and the optimization of DART conditions. The results showed consistent signal changes and high tolerance of nonvolatile salts of this SPR-MS system, demonstrating the feasibility of the interface for online coupling of SPR with MS and the potential application in the characterization of interaction under physiological conditions.</description><identifier>ISSN: 0003-2700</identifier><identifier>EISSN: 1520-6882</identifier><identifier>DOI: 10.1021/acs.analchem.5b01272</identifier><identifier>PMID: 26067340</identifier><identifier>CODEN: ANCHAM</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><subject>Analytical chemistry ; Dissolution ; Joining ; Mass spectrometry ; Mass Spectrometry - methods ; Online ; Optimization ; Plasmons ; Real time ; Sampling ; Surface Plasmon Resonance - methods</subject><ispartof>Analytical chemistry (Washington), 2015-07, Vol.87 (13), p.6505-6509</ispartof><rights>Copyright © American Chemical Society</rights><rights>Copyright American Chemical Society Jul 7, 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a409t-a87d99b11115187bc6bc43079d6cb7c3d0d110507d506a87fd464da6371f8fb43</citedby><cites>FETCH-LOGICAL-a409t-a87d99b11115187bc6bc43079d6cb7c3d0d110507d506a87fd464da6371f8fb43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/acs.analchem.5b01272$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/acs.analchem.5b01272$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,776,780,2751,27055,27903,27904,56716,56766</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26067340$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Yiding</creatorcontrib><creatorcontrib>Li, Xianjiang</creatorcontrib><creatorcontrib>Nie, Honggang</creatorcontrib><creatorcontrib>Yang, Li</creatorcontrib><creatorcontrib>Li, Ze</creatorcontrib><creatorcontrib>Bai, Yu</creatorcontrib><creatorcontrib>Niu, Li</creatorcontrib><creatorcontrib>Song, Daqian</creatorcontrib><creatorcontrib>Liu, Huwei</creatorcontrib><title>Interface for Online Coupling of Surface Plasmon Resonance to Direct Analysis in Real Time Mass Spectrometry</title><title>Analytical chemistry (Washington)</title><addtitle>Anal. Chem</addtitle><description>The online coupling of surface plasmon resonance (SPR) with mass spectrometry (MS) has been highly desired for the complementary information provided by each of the two techniques. In this work, a novel interface for direct and online coupling of SPR to direct analysis in real time (DART) MS was developed. A spray tip connected with the outlet of the SPR flow solution was conducted as the sampling part of the DART-MS, with which the online coupling interface of SPR-MS was realized. Four model samples, acetaminophen, metronidazole, quinine, and hippuric acid, dissolved in three kinds of common buffers were used in the SPR-DART-MS experiments for performance evaluation of the interface and the optimization of DART conditions. The results showed consistent signal changes and high tolerance of nonvolatile salts of this SPR-MS system, demonstrating the feasibility of the interface for online coupling of SPR with MS and the potential application in the characterization of interaction under physiological conditions.</description><subject>Analytical chemistry</subject><subject>Dissolution</subject><subject>Joining</subject><subject>Mass spectrometry</subject><subject>Mass Spectrometry - methods</subject><subject>Online</subject><subject>Optimization</subject><subject>Plasmons</subject><subject>Real time</subject><subject>Sampling</subject><subject>Surface Plasmon Resonance - methods</subject><issn>0003-2700</issn><issn>1520-6882</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkV1PwyAUhonRuPnxD4wh8cabzgNtob1c5teSmRk3rxtKqXahZUJ7sX8vs5smXig3EM7zvpzDi9AFgREBSm6EdCPRCC3fVT2KcyCU0wM0JDGFgCUJPURDAAgDygEG6MS5FQAhQNgxGlAGjIcRDJGeNq2ypZAKl8bieaOrRuGJ6db-8IZNiRddX37WwtWmwS_KmUY0_qY1-LaySrZ47PvYuMrhalsXGi-rWuEn4RxerD1gTa1auzlDR6XQTp3v9lP0en-3nDwGs_nDdDKeBSKCtA1Ewos0zYlfMUl4LlkuoxB4WjCZcxkWUPhBYuBFDMzDZRGxqBAs5KRMyjwKT9F177u25qNTrs3qykmltWiU6VxGOElS_wWU_Y-yNEoZDRnx6NUvdGU66yf_omKegO_JU1FPSWucs6rM1raqhd1kBLJtcJkPLtsHl-2C87LLnXmX16r4Fu2T8gD0wFb-8_Bfnp_5Y6Yo</recordid><startdate>20150707</startdate><enddate>20150707</enddate><creator>Zhang, Yiding</creator><creator>Li, Xianjiang</creator><creator>Nie, Honggang</creator><creator>Yang, Li</creator><creator>Li, Ze</creator><creator>Bai, Yu</creator><creator>Niu, Li</creator><creator>Song, Daqian</creator><creator>Liu, Huwei</creator><general>American Chemical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7TM</scope><scope>7U5</scope><scope>7U7</scope><scope>7U9</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>H94</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20150707</creationdate><title>Interface for Online Coupling of Surface Plasmon Resonance to Direct Analysis in Real Time Mass Spectrometry</title><author>Zhang, Yiding ; Li, Xianjiang ; Nie, Honggang ; Yang, Li ; Li, Ze ; Bai, Yu ; Niu, Li ; Song, Daqian ; Liu, Huwei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a409t-a87d99b11115187bc6bc43079d6cb7c3d0d110507d506a87fd464da6371f8fb43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Analytical chemistry</topic><topic>Dissolution</topic><topic>Joining</topic><topic>Mass spectrometry</topic><topic>Mass Spectrometry - methods</topic><topic>Online</topic><topic>Optimization</topic><topic>Plasmons</topic><topic>Real time</topic><topic>Sampling</topic><topic>Surface Plasmon Resonance - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Yiding</creatorcontrib><creatorcontrib>Li, Xianjiang</creatorcontrib><creatorcontrib>Nie, Honggang</creatorcontrib><creatorcontrib>Yang, Li</creatorcontrib><creatorcontrib>Li, Ze</creatorcontrib><creatorcontrib>Bai, Yu</creatorcontrib><creatorcontrib>Niu, Li</creatorcontrib><creatorcontrib>Song, Daqian</creatorcontrib><creatorcontrib>Liu, Huwei</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Analytical chemistry (Washington)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Yiding</au><au>Li, Xianjiang</au><au>Nie, Honggang</au><au>Yang, Li</au><au>Li, Ze</au><au>Bai, Yu</au><au>Niu, Li</au><au>Song, Daqian</au><au>Liu, Huwei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Interface for Online Coupling of Surface Plasmon Resonance to Direct Analysis in Real Time Mass Spectrometry</atitle><jtitle>Analytical chemistry (Washington)</jtitle><addtitle>Anal. Chem</addtitle><date>2015-07-07</date><risdate>2015</risdate><volume>87</volume><issue>13</issue><spage>6505</spage><epage>6509</epage><pages>6505-6509</pages><issn>0003-2700</issn><eissn>1520-6882</eissn><coden>ANCHAM</coden><abstract>The online coupling of surface plasmon resonance (SPR) with mass spectrometry (MS) has been highly desired for the complementary information provided by each of the two techniques. In this work, a novel interface for direct and online coupling of SPR to direct analysis in real time (DART) MS was developed. A spray tip connected with the outlet of the SPR flow solution was conducted as the sampling part of the DART-MS, with which the online coupling interface of SPR-MS was realized. Four model samples, acetaminophen, metronidazole, quinine, and hippuric acid, dissolved in three kinds of common buffers were used in the SPR-DART-MS experiments for performance evaluation of the interface and the optimization of DART conditions. The results showed consistent signal changes and high tolerance of nonvolatile salts of this SPR-MS system, demonstrating the feasibility of the interface for online coupling of SPR with MS and the potential application in the characterization of interaction under physiological conditions.</abstract><cop>United States</cop><pub>American Chemical Society</pub><pmid>26067340</pmid><doi>10.1021/acs.analchem.5b01272</doi><tpages>5</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0003-2700 |
ispartof | Analytical chemistry (Washington), 2015-07, Vol.87 (13), p.6505-6509 |
issn | 0003-2700 1520-6882 |
language | eng |
recordid | cdi_proquest_miscellaneous_1718960626 |
source | ACS Publications; MEDLINE |
subjects | Analytical chemistry Dissolution Joining Mass spectrometry Mass Spectrometry - methods Online Optimization Plasmons Real time Sampling Surface Plasmon Resonance - methods |
title | Interface for Online Coupling of Surface Plasmon Resonance to Direct Analysis in Real Time Mass Spectrometry |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T07%3A15%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Interface%20for%20Online%20Coupling%20of%20Surface%20Plasmon%20Resonance%20to%20Direct%20Analysis%20in%20Real%20Time%20Mass%20Spectrometry&rft.jtitle=Analytical%20chemistry%20(Washington)&rft.au=Zhang,%20Yiding&rft.date=2015-07-07&rft.volume=87&rft.issue=13&rft.spage=6505&rft.epage=6509&rft.pages=6505-6509&rft.issn=0003-2700&rft.eissn=1520-6882&rft.coden=ANCHAM&rft_id=info:doi/10.1021/acs.analchem.5b01272&rft_dat=%3Cproquest_cross%3E1694962361%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1695780050&rft_id=info:pmid/26067340&rfr_iscdi=true |