Estimation of patient radiation dose from whole body super(18)F-FDG PET/CT examination in cancer imaging: a preliminary study
This study aims to estimate the radiation effective dose resulting from whole body fluorine-18 flourodeoxyglucose Positron Emission Tomography ( super(18)F-FDG PET) scanning as compared to conservative Computed Tomography (CT) techniques in evaluating oncology patients. We reviewed 19 oncology patie...
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Veröffentlicht in: | Journal of physics. Conference series 2014-01, Vol.546, p.1-6 |
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creator | Mahmud, M H Nordin, A J Saad, F F Ahmad Azman, A Z Fattah |
description | This study aims to estimate the radiation effective dose resulting from whole body fluorine-18 flourodeoxyglucose Positron Emission Tomography ( super(18)F-FDG PET) scanning as compared to conservative Computed Tomography (CT) techniques in evaluating oncology patients. We reviewed 19 oncology patients who underwent super(18)F-FDG PET/CT at our centre for cancer staging. Internal and external doses were estimated using radioactivity of injected FDG and volume CT Dose Index (CTDI sub(vol)), respectively with employment of the published and modified dose coefficients. The median differences of dose among the conservative CT and PET protocols were determined using Kruskal Wallis test with p < 0.05 considered as significant. The median (interquartile range, IQR) effective doses of non-contrasted CT, contrasted CT and PET scanning protocols were 7.50 (9.35) mSv, 9.76 (3.67) mSv and 6.30 (1.20) mSv, respectively, resulting in the total dose of 21.46 (8.58) mSv. Statistically significant difference was observed in the median effective dose between the three protocols (p < 0.01). The effective doses of whole body super(18)F-FDG PET technique may be effective the lowest amongst the conventional CT imaging techniques. |
doi_str_mv | 10.1088/1742-6596/546/1/012008 |
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We reviewed 19 oncology patients who underwent super(18)F-FDG PET/CT at our centre for cancer staging. Internal and external doses were estimated using radioactivity of injected FDG and volume CT Dose Index (CTDI sub(vol)), respectively with employment of the published and modified dose coefficients. The median differences of dose among the conservative CT and PET protocols were determined using Kruskal Wallis test with p < 0.05 considered as significant. The median (interquartile range, IQR) effective doses of non-contrasted CT, contrasted CT and PET scanning protocols were 7.50 (9.35) mSv, 9.76 (3.67) mSv and 6.30 (1.20) mSv, respectively, resulting in the total dose of 21.46 (8.58) mSv. Statistically significant difference was observed in the median effective dose between the three protocols (p < 0.01). The effective doses of whole body super(18)F-FDG PET technique may be effective the lowest amongst the conventional CT imaging techniques.</description><identifier>ISSN: 1742-6588</identifier><identifier>EISSN: 1742-6596</identifier><identifier>DOI: 10.1088/1742-6596/546/1/012008</identifier><language>eng</language><subject>Cancer ; Computer aided tomography ; Estimates ; Patients ; Positron emission ; Radioactivity ; Scanning ; Tomography</subject><ispartof>Journal of physics. 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Conference series</title><description>This study aims to estimate the radiation effective dose resulting from whole body fluorine-18 flourodeoxyglucose Positron Emission Tomography ( super(18)F-FDG PET) scanning as compared to conservative Computed Tomography (CT) techniques in evaluating oncology patients. We reviewed 19 oncology patients who underwent super(18)F-FDG PET/CT at our centre for cancer staging. Internal and external doses were estimated using radioactivity of injected FDG and volume CT Dose Index (CTDI sub(vol)), respectively with employment of the published and modified dose coefficients. The median differences of dose among the conservative CT and PET protocols were determined using Kruskal Wallis test with p < 0.05 considered as significant. The median (interquartile range, IQR) effective doses of non-contrasted CT, contrasted CT and PET scanning protocols were 7.50 (9.35) mSv, 9.76 (3.67) mSv and 6.30 (1.20) mSv, respectively, resulting in the total dose of 21.46 (8.58) mSv. Statistically significant difference was observed in the median effective dose between the three protocols (p < 0.01). The effective doses of whole body super(18)F-FDG PET technique may be effective the lowest amongst the conventional CT imaging techniques.</description><subject>Cancer</subject><subject>Computer aided tomography</subject><subject>Estimates</subject><subject>Patients</subject><subject>Positron emission</subject><subject>Radioactivity</subject><subject>Scanning</subject><subject>Tomography</subject><issn>1742-6588</issn><issn>1742-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqVTD1PwzAUtBBIFOhfQG8sQ7CdtonLWhI6dshemeSlNXLs4OcIOvDfSVXUnVvudF-MPUrxLIVSXOaLNMmWq4wvFxmXXMhUCHXFJpfg-qKVumV3RB9CzEfkE_ZTUDSdjsY78C30o0IXIejGnM3GE0IbfAdfB28R3n1zBBp6DDOpnsqkfH2DbVHxdQX4rTvjzjPjoNauxgDj-964_Qto6ANac6qE8SIOzfGB3bTaEk7_-J7NyqJab5I--M8BKe46QzVaqx36gXYyl2qVqjQT839UfwGlCVm0</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Mahmud, M H</creator><creator>Nordin, A J</creator><creator>Saad, F F Ahmad</creator><creator>Azman, A Z Fattah</creator><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>H8D</scope><scope>JG9</scope><scope>L7M</scope></search><sort><creationdate>20140101</creationdate><title>Estimation of patient radiation dose from whole body super(18)F-FDG PET/CT examination in cancer imaging: a preliminary study</title><author>Mahmud, M H ; Nordin, A J ; Saad, F F Ahmad ; Azman, A Z Fattah</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_17189282603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Cancer</topic><topic>Computer aided tomography</topic><topic>Estimates</topic><topic>Patients</topic><topic>Positron emission</topic><topic>Radioactivity</topic><topic>Scanning</topic><topic>Tomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mahmud, M H</creatorcontrib><creatorcontrib>Nordin, A J</creatorcontrib><creatorcontrib>Saad, F F Ahmad</creatorcontrib><creatorcontrib>Azman, A Z Fattah</creatorcontrib><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Journal of physics. Conference series</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mahmud, M H</au><au>Nordin, A J</au><au>Saad, F F Ahmad</au><au>Azman, A Z Fattah</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Estimation of patient radiation dose from whole body super(18)F-FDG PET/CT examination in cancer imaging: a preliminary study</atitle><jtitle>Journal of physics. Conference series</jtitle><date>2014-01-01</date><risdate>2014</risdate><volume>546</volume><spage>1</spage><epage>6</epage><pages>1-6</pages><issn>1742-6588</issn><eissn>1742-6596</eissn><abstract>This study aims to estimate the radiation effective dose resulting from whole body fluorine-18 flourodeoxyglucose Positron Emission Tomography ( super(18)F-FDG PET) scanning as compared to conservative Computed Tomography (CT) techniques in evaluating oncology patients. We reviewed 19 oncology patients who underwent super(18)F-FDG PET/CT at our centre for cancer staging. Internal and external doses were estimated using radioactivity of injected FDG and volume CT Dose Index (CTDI sub(vol)), respectively with employment of the published and modified dose coefficients. The median differences of dose among the conservative CT and PET protocols were determined using Kruskal Wallis test with p < 0.05 considered as significant. The median (interquartile range, IQR) effective doses of non-contrasted CT, contrasted CT and PET scanning protocols were 7.50 (9.35) mSv, 9.76 (3.67) mSv and 6.30 (1.20) mSv, respectively, resulting in the total dose of 21.46 (8.58) mSv. Statistically significant difference was observed in the median effective dose between the three protocols (p < 0.01). The effective doses of whole body super(18)F-FDG PET technique may be effective the lowest amongst the conventional CT imaging techniques.</abstract><doi>10.1088/1742-6596/546/1/012008</doi></addata></record> |
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subjects | Cancer Computer aided tomography Estimates Patients Positron emission Radioactivity Scanning Tomography |
title | Estimation of patient radiation dose from whole body super(18)F-FDG PET/CT examination in cancer imaging: a preliminary study |
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