Functional chondroitin sulfate from Enteroctopus dofleini containing a 3-O-sulfo glucuronic acid residue

•CS containing 13.9% of K-type units was found in Enteroctopus dofleini.•Population of fucosylated disaccharide units in octopus CS-K was low.•Octopus CS-K promoted neurite outgrowth activity in hippocampal neurons.•Octopus CS-K showed high affinity for growth factors. There are several reports that...

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Veröffentlicht in:	Carbohydrate polymers 2015-12, Vol.134, p.557-565
Hauptverfasser:	Higashi, Kyohei, Okamoto, Yusuke, Mukuno, Ann, Wakai, Jun, Hosoyama, Saori, Linhardt, Robert J., Toida, Toshihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cartilage - chemistry Chondroitin sulfate Chondroitin Sulfates - chemistry Chondroitin Sulfates - pharmacology Glucuronic Acid - analysis Growth factors Hippocampus - cytology K-unit Mice Neurites - drug effects Neurites - metabolism Octopodiformes - chemistry Octopus cartilage
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