First human challenge testing of a pneumococcal vaccine. Double-blind randomized controlled trial

New vaccines are urgently needed to protect the vulnerable from bacterial pneumonia. Clinical trials of pneumonia vaccines are slow and costly, requiring tens of thousands of patients. Studies of pneumococcal vaccine efficacy against colonization have been proposed as a novel method to down-select b...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2015-10, Vol.192 (7), p.853-858
Hauptverfasser:	Collins, Andrea M, Wright, Angela D, Mitsi, Elena, Gritzfeld, Jenna F, Hancock, Carole A, Pennington, Shaun H, Wang, Duolao, Morton, Ben, Ferreira, Daniela M, Gordon, Stephen B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Double-Blind Method Healthy Volunteers Humans Middle Aged Pneumococcal Vaccines Pneumonia, Pneumococcal - prevention & control Vaccines, Conjugate Young Adult
Online-Zugang:	Volltext
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