miR-31 functions as an oncogene in cervical cancer

Background MicroRNAs are frequently altered in numerous cancers and are critical regulators of various diseases. miR-31 has been shown to be significantly altered in a variety of cancers. Methods In the present study, we measured the expression level of miR-31 in cervical cancer, CIN and normal cerv...

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Veröffentlicht in:	Archives of gynecology and obstetrics 2015-11, Vol.292 (5), p.1083-1089
Hauptverfasser:	Zheng, Wenjing, Liu, Zhen, Zhang, Wei, Hu, Xiaoxia
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biomarkers, Tumor - metabolism Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Case-Control Studies Cell growth Cell Proliferation - drug effects Cell Transformation, Neoplastic - metabolism Cervical cancer Cervical Intraepithelial Neoplasia - genetics Cervical Intraepithelial Neoplasia - metabolism Endocrinology Female Gynecologic Oncology Gynecology HeLa Cells Human Genetics Human papillomavirus Humans Lymphatic Metastasis - genetics Medicine Medicine & Public Health MicroRNAs - metabolism Obstetrics/Perinatology/Midwifery Oncogene Proteins, Viral - genetics Oncogene Proteins, Viral - metabolism Papillomavirus E7 Proteins - metabolism Repressor Proteins - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Small Interfering Signal Transduction - physiology Transfection Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - metabolism
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