ORIGINAL ARTICLE: Nifedipine inhibits picrotoxin-induced seizure activity: further evidence on the involvement of L-type calcium channel blockers in epilepsy

A large body of evidence supports the role of L-type calcium channels in epileptogenesis. The aim of the present study was to study the efficacy of the specific L-type calcium channel blocker nifedipine on seizure activity induced by picrotoxin (PTX). Adult female Sprague-Dawley rats were used in th...

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Veröffentlicht in:Fundamental & clinical pharmacology 2006-04, Vol.20 (2), p.115-119
Hauptverfasser: Otoom, Sameer, Hasan, Zuhair
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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