Long-term changes in the aggregation state and toxic effects of β-amyloid injected into the rat brain

The long-term effects of β-amyloid peptide 1–40 injection into the rat forebrain were studied. Ten micrograms of pre-aggregated peptide were injected into the right nucleus basalis of male Wistar rats which were then killed four or six months later. Congo Red staining of histological sections showed...

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