Effects of Atorvastatin on Resting and Peak Exercise Blood Pressure
To determine if 80mg of atorvastatin reduces resting BP and peak systolic BP (SBP) on a graded exercise test. Subjects were double-blinded and randomized to 80mg times d-1 of atorvastatin (n=202) or placebo (n=217) for 6 months. Resting BP and peak SBP were measured by auscultation at baseline and 6...
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| Veröffentlicht in: | Medicine and science in sports and exercise 2012-05, Vol.44 (5S), p.894-894 |
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| container_title | Medicine and science in sports and exercise |
| container_volume | 44 |
| creator | Mentch, Marianne L Parker, Beth A Capizzi, Jeffrey A Grimaldi, Adam S Clarkson, Priscilla M Cole, Stephanie M Chipkin, Stuart Keadle, Justin White, C Michael Thompson, Paul D Pescatello, Linda S |
| description | To determine if 80mg of atorvastatin reduces resting BP and peak systolic BP (SBP) on a graded exercise test. Subjects were double-blinded and randomized to 80mg times d-1 of atorvastatin (n=202) or placebo (n=217) for 6 months. Resting BP and peak SBP were measured by auscultation at baseline and 6 months. Repeated measures ANCOVA tested differences in resting BP and peak SBP over 6 months by drug treatment group and gender with age and body mass index (BMI) as covariates. Subjects were 44.1 + or - 0.8 yr (mean + or - SEM) with resting BP of 118.9 + or - 0.6/75.3 + or - 0.5 mmHg and BMI of 26.4 + or - 0.2 kg[midot]m-2. Men (n=203) had higher resting BP (121.6 + or - 0.9/76.5 + or - 0.7 vs. 116.2 + or - 0.9/74.1 + or - 0.7 mmHg) and peak SBP (177.5 + or - 1.9 vs. 161.3 + or - 1.7 mmHg) than women (n=216) (p=0.000). |
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| language | eng |
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| source | Journals@Ovid LWW Legacy Archive; Journals@Ovid Complete |
| title | Effects of Atorvastatin on Resting and Peak Exercise Blood Pressure |
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