Treatment responsiveness of phenotypes of symptomatic airways obstruction in adults

Background Asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous disorders encompassing different phenotypes of airflow obstruction, which might differ in their response to treatment. Objective The aim of this study was to determine distinct phenotypes comprising the syndromes of...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2015-09, Vol.136 (3), p.601-609
Hauptverfasser:	Fingleton, James, PhD, Travers, Justin, MBChB, Williams, Mathew, Dip Ex Sci, Charles, Thomas, DipSM, Bowles, Darren, MBChB, Strik, Rianne, BSc, Shirtcliffe, Philippa, MBChB, Weatherall, Mark, MBChB, Beasley, Richard, DSc
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adrenergic beta-2 Receptor Agonists - therapeutic use Adult Aged Airway Obstruction - complications Airway Obstruction - drug therapy Airway Obstruction - pathology Albuterol - therapeutic use Allergy and Immunology Anti-Asthmatic Agents - therapeutic use Asthma Asthma - complications Asthma - drug therapy Asthma - pathology Biomarkers bronchodilator Budesonide - therapeutic use Chronic obstructive pulmonary disease Cluster Analysis Disease control Female Gastroesophageal reflux Genotype & phenotype Glucocorticoids - therapeutic use Humans inhaled corticosteroid Ipratropium - therapeutic use Male Middle Aged Muscarinic Antagonists - therapeutic use Nitric oxide Obesity - complications Obesity - drug therapy Obesity - pathology Phenotype Pulmonary Disease, Chronic Obstructive - complications Pulmonary Disease, Chronic Obstructive - drug therapy Pulmonary Disease, Chronic Obstructive - pathology Questionnaires Risk factors Severity of Illness Index Surveys and Questionnaires Treatment Outcome
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