Positive Recognition of MHC Class I Molecules by the Ly49D Receptor of Murine NK Cells

Members of the murine Ly49 family of receptors have been shown to inhibit and activate NK cell function. Subsets of Ly49-expressing NK cells mediate the rejection of bone marrow cell allografts and the lysis of allogeneic lymphoblasts. In this report we have studied Ly49-mediated positive and negati...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of immunology (1950) 1999-02, Vol.162 (4), p.2035-2043
Hauptverfasser:	George, Thaddeus C, Mason, Llewellyn H, Ortaldo, John R, Kumar, Vinay, Bennett, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - metabolism Antibodies, Monoclonal - pharmacology Antigens, Ly Cell Separation Concanavalin A - immunology Cross Reactions Cytotoxicity Tests, Immunologic Cytotoxicity, Immunologic H-2 Antigens - immunology H-2 Antigens - metabolism Killer Cells, Natural - cytology Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Lectins, C-Type Lymphocyte Activation - immunology Lymphocyte Subsets - cytology Lymphocyte Subsets - immunology Membrane Glycoproteins - metabolism Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic NK Cell Lectin-Like Receptor Subfamily A Receptors, Immunologic - immunology Receptors, Immunologic - metabolism Receptors, Immunologic - physiology Receptors, NK Cell Lectin-Like Species Specificity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!