The cAMP-specific phosphodiesterase 4B mediates Aβ-induced microglial activation

Microglial activation is a key player in the degenerative process that accompanies the deposition of amyloid-β (Aβ) peptide into senile plaques in Alzheimer's disease (AD) patients. The goal of this study is to identify novel genes involved in microglial activation in response to Aβ peptide. Pr...

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Veröffentlicht in:	Neurobiology of aging 2006-05, Vol.27 (5), p.691-701
Hauptverfasser:	Sebastiani, Giovanna, Morissette, Céline, Lagacé, Caroline, Boulé, Marie, Ouellette, Marie-Josée, McLaughlin, Richard W., Lacombe, Diane, Gervais, Francine, Tremblay, Patrick
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Array analysis Pde4B Primary rat microglial activation
Online-Zugang:	Volltext
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