Protein Interactions of Src Homology 2 (SH2) Domain-Containing Inositol Phosphatase (SHIP): Association with Shc Displaces SHIP from FcγRIIb in B Cells

Our recent studies revealed that the inositol phosphatase Src homology 2 (SH2) domain-containing inositol phosphatase (SHIP) is phosphorylated and associated with Shc exclusively under negative signaling conditions in B cells, which is due to recruitment of the SHIP SH2 domain to the FcγRIIb. In add...

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Veröffentlicht in:The Journal of immunology (1950) 1999-02, Vol.162 (3), p.1408-1414
Hauptverfasser: Tridandapani, Susheela, Pradhan, Madhura, LaDine, James R., Garber, Stacey, Anderson, Clark L., Coggeshall, K. Mark
Format: Artikel
Sprache:eng
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