An overview of triple negative breast cancer for surgical oncologists

Abstract Triple negative breast cancers (TNBCs) represent a distinct subgroup of breast cancers with an immunohistochemical phenotype that is negative for oestrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2). The aim of this article is to provide...

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Veröffentlicht in:	Surgical oncology 2015-09, Vol.24 (3), p.276-283
Hauptverfasser:	Sharma, Shiva, Barry, Mitchel, Gallagher, David J, Kell, Malcolm, Sacchini, Virgilio
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Angiogenesis Apoptosis Breast cancer Breast surgery oncology Cancer therapies Cell cycle Chemotherapy Conflicts of interest Epidemiology Epidermal growth factor Female Gene expression Hematology, Oncology and Palliative Medicine Humans Investigations Kinases Medical prognosis Metastasis Molecular biology Morphology Mutation Prognosis Receptor, ErbB-2 - metabolism Receptors, Estrogen - metabolism Receptors, Progesterone - metabolism Review Signal transduction Surgery Triple negative breast cancer Triple Negative Breast Neoplasms - diagnosis Triple Negative Breast Neoplasms - metabolism Triple Negative Breast Neoplasms - therapy Tumors Womens health
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